Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DMGDH
  • Mouse genes Dmgdh
  • Rat genes Dmgdh
  • Zfish genes dmgdh
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dmgdh

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0047865	dimethylglycine dehydrogenase activity	DMGDH	IMP		Human	PMID:11231903
Molecular Function	GO:0047865	dimethylglycine dehydrogenase activity	Dmgdh	IDA		Rat	PMID:1710985|RGD:632576
Molecular Function	GO:0047865	dimethylglycine dehydrogenase activity	Dmgdh	IDA		Rat	PMID:6159630|RGD:1599787
Molecular Function	GO:0047865	dimethylglycine dehydrogenase activity	Dmgdh	IDA		Rat	PMID:6163778|RGD:7245485
Molecular Function	GO:0050660	flavin adenine dinucleotide binding	Dmgdh	IDA		Rat	PMID:6163778|RGD:7245485
Molecular Function	GO:0050660	flavin adenine dinucleotide binding	Dmgdh	IDA		Rat	PMID:8621665|RGD:1599785
Molecular Function	GO:0005542	folic acid binding	Dmgdh	IDA		Rat	PMID:6159630|RGD:1599787
Molecular Function	GO:0005542	folic acid binding	Dmgdh	IDA		Rat	PMID:6163778|RGD:7245485
Molecular Function	GO:0003723	RNA binding	DMGDH	HDA		Human	PMID:22658674
Cellular Component	GO:0005739	mitochondrion	DMGDH	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	Dmgdh	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Dmgdh	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Dmgdh	IDA		Rat	PMID:6159630|RGD:1599787
Cellular Component	GO:0005739	mitochondrion	Dmgdh	IDA		Rat	PMID:6163778|RGD:7245485
Cellular Component	GO:0005739	mitochondrion	Dmgdh	IDA		Rat	PMID:8621665|RGD:1599785
Biological Process	GO:0042426	choline catabolic process	DMGDH	IMP		Human	PMID:10102904
Biological Process	GO:0035999	tetrahydrofolate interconversion	Dmgdh	IDA		Rat	PMID:6163778|RGD:7245485

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern