Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DLK2
  • Mouse genes Dlk2
  • Rat genes Dlk2
  • Zfish genes dlk2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dlk2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	Dlk2	IPI	PR:Q8K1E3	Mouse	PMID:21419176
Molecular Function	GO:0005515	protein binding	Dlk2	IPI	PR:Q09163	Mouse	PMID:21419176
Molecular Function	GO:0005515	protein binding	Dlk2	IPI	PR:Q01705	Mouse	PMID:21419176
Biological Process	GO:0016525	negative regulation of angiogenesis	dlk2	IMP	ZFIN:ZDB-MRPHLNO-140123-8	Zfish	PMID:22068159
Biological Process	GO:0045746	negative regulation of Notch signaling pathway	DLK2	IDA		Human	PMID:25093684
Biological Process	GO:0045746	negative regulation of Notch signaling pathway	Dlk2	IGI	MGI:MGI:97363	Mouse	PMID:21419176
Biological Process	GO:0045746	negative regulation of Notch signaling pathway	dlk2	IMP	ZFIN:ZDB-MRPHLNO-140123-8	Zfish	PMID:22068159
Biological Process	GO:0045598	regulation of fat cell differentiation	Dlk2	IDA		Mouse	MGI:MGI:3709915|PMID:17320102
Biological Process	GO:0001944	vasculature development	dlk2	IMP	ZFIN:ZDB-MRPHLNO-140123-8	Zfish	PMID:22068159

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern