Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DIS3L2
  • Mouse genes Dis3l2
  • Rat genes Dis3l2
  • Zfish genes dis3l2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dis3l2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0000175	3'-5'-RNA exonuclease activity	DIS3L2	IDA		Human	PMID:23756462
Molecular Function	GO:0000175	3'-5'-RNA exonuclease activity	DIS3L2	IDA		Human	PMID:24141620
Molecular Function	GO:0000175	3'-5'-RNA exonuclease activity	Dis3l2	IDA		Mouse	MGI:MGI:5603455|PMID:25119025
Molecular Function	GO:0000175	3'-5'-RNA exonuclease activity	Dis3l2	IDA		Mouse	MGI:MGI:5494337|PMID:23594738
Molecular Function	GO:0000287	magnesium ion binding	DIS3L2	IDA		Human	PMID:24141620
Molecular Function	GO:0000287	magnesium ion binding	Dis3l2	IDA		Mouse	MGI:MGI:5603455|PMID:25119025
Molecular Function	GO:0008266	poly(U) RNA binding	DIS3L2	IDA		Human	PMID:24141620
Molecular Function	GO:0008266	poly(U) RNA binding	Dis3l2	IDA		Mouse	MGI:MGI:5603455|PMID:25119025
Molecular Function	GO:0005515	protein binding	DIS3L2	IPI	UniProtKB:Q8IZH2	Human	PMID:23756462
Molecular Function	GO:0005515	protein binding	Dis3l2	IPI	UniProtKB:Q8K3Y3	Mouse	MGI:MGI:5494337|PMID:23594738
Molecular Function	GO:0004540	RNA nuclease activity	DIS3L2	IDA		Human	PMID:22306653
Cellular Component	GO:0005737	cytoplasm	DIS3L2	IDA		Human	PMID:22306653
Cellular Component	GO:0005737	cytoplasm	DIS3L2	IDA		Human	PMID:23756462
Cellular Component	GO:0005737	cytoplasm	DIS3L2	IDA		Human	PMID:24141620
Cellular Component	GO:0005737	cytoplasm	Dis3l2	IDA		Mouse	MGI:MGI:5494337|PMID:23594738
Cellular Component	GO:0005737	cytoplasm	Dis3l2	IDA		Mouse	MGI:MGI:5603455|PMID:25119025
Cellular Component	GO:0000932	P-body	DIS3L2	IDA		Human	PMID:23756462
Biological Process	GO:0010587	miRNA catabolic process	DIS3L2	IDA		Human	PMID:24141620
Biological Process	GO:0010587	miRNA catabolic process	Dis3l2	IDA		Mouse	MGI:MGI:5603455|PMID:25119025
Biological Process	GO:0010587	miRNA catabolic process	Dis3l2	IMP		Mouse	MGI:MGI:5494337|PMID:23594738
Biological Process	GO:0000278	mitotic cell cycle	DIS3L2	IMP		Human	PMID:22306653
Biological Process	GO:0051306	mitotic sister chromatid separation	DIS3L2	IMP		Human	PMID:22306653
Biological Process	GO:0008285	negative regulation of cell population proliferation	DIS3L2	IMP		Human	PMID:22306653
Biological Process	GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic	DIS3L2	IMP		Human	PMID:23756462
Biological Process	GO:0048793	pronephros development	dis3l2	IMP	ZFIN:ZDB-MRPHLNO-131220-1	Zfish	PMID:22306653
Biological Process	GO:0048793	pronephros development	dis3l2	IMP	ZFIN:ZDB-MRPHLNO-131220-2	Zfish	PMID:22306653
Biological Process	GO:0019827	stem cell population maintenance	Dis3l2	IMP		Mouse	MGI:MGI:5494337|PMID:23594738

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern