Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DIO1
  • Mouse genes Dio1
  • Rat genes Dio1
  • Zfish genes dio1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dio1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008430	selenium binding	Dio1	IDA		Mouse	PMID:8419134
Molecular Function	GO:0004800	thyroxine 5'-deiodinase activity	Dio1	IDA		Mouse	MGI:MGI:3691903|PMID:12586753
Molecular Function	GO:0004800	thyroxine 5'-deiodinase activity	Dio1	IDA		Mouse	PMID:8419134
Molecular Function	GO:0004800	thyroxine 5'-deiodinase activity	Dio1	IDA		Rat	PMID:1825132|RGD:728721
Biological Process	GO:0006520	amino acid metabolic process	DIO1	IGI	UniProtKB:P36021	Human	PMID:26305885
Biological Process	GO:0061074	regulation of neural retina development	dio1	IGI	ZFIN:ZDB-MRPHLNO-091028-1,ZFIN:ZDB-MRPHLNO-100525-3	Zfish	PMID:26802877

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern