Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DIAPH2
  • Mouse genes Diaph2
  • Rat genes Diaph2
  • Zfish genes diaph2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Diaph2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	Diaph2	IDA		Mouse	PMID:14992721
Cellular Component	GO:0005783	endoplasmic reticulum	DIAPH2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	DIAPH2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	DIAPH2	IDA		Human	GO_REF:0000052
Biological Process	GO:0030041	actin filament polymerization	Diaph2	IDA		Mouse	PMID:14992721
Biological Process	GO:0030041	actin filament polymerization	diaph2	IMP	ZFIN:ZDB-MRPHLNO-090115-2	Zfish	PMID:18941507
Biological Process	GO:0042074	cell migration involved in gastrulation	diaph2	IMP	ZFIN:ZDB-MRPHLNO-090115-2	Zfish	PMID:18941507
Biological Process	GO:0060027	convergent extension involved in gastrulation	diaph2	IGI	ZFIN:ZDB-MRPHLNO-090115-2,ZFIN:ZDB-MRPHLNO-090115-3	Zfish	PMID:18941507
Biological Process	GO:0060027	convergent extension involved in gastrulation	diaph2	IMP	ZFIN:ZDB-MRPHLNO-090115-1	Zfish	PMID:18941507
Biological Process	GO:0060027	convergent extension involved in gastrulation	diaph2	IMP	ZFIN:ZDB-MRPHLNO-090115-2	Zfish	PMID:18941507
Biological Process	GO:0055113	epiboly involved in gastrulation with mouth forming second	diaph2	IMP	ZFIN:ZDB-MRPHLNO-090115-2	Zfish	PMID:18941507
Biological Process	GO:0055113	epiboly involved in gastrulation with mouth forming second	diaph2	IGI	ZFIN:ZDB-MRPHLNO-090115-2,ZFIN:ZDB-MRPHLNO-090115-3	Zfish	PMID:18941507
Biological Process	GO:0055113	epiboly involved in gastrulation with mouth forming second	diaph2	IMP	ZFIN:ZDB-MRPHLNO-090115-1	Zfish	PMID:18941507
Biological Process	GO:0040001	establishment of mitotic spindle localization	diaph2	IMP	ZFIN:ZDB-MRPHLNO-090115-1	Zfish	PMID:23201782
Biological Process	GO:0051056	regulation of small GTPase mediated signal transduction	diaph2	IGI	ZFIN:ZDB-MRPHLNO-090115-1,ZFIN:ZDB-MRPHLNO-150928-1	Zfish	PMID:26086034

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern