Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DHRS2
  • Mouse genes Dhrs2
  • Rat genes Dhrs2
  • Zfish genes dhrs4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dhrs2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004090	carbonyl reductase (NADPH) activity	DHRS2	IDA		Human	PMID:16685466
Molecular Function	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	DHRS2	IDA		Human	PMID:16685466
Molecular Function	GO:0005515	protein binding	DHRS2	IPI	UniProtKB:Q92624	Human	PMID:25416956
Cellular Component	GO:0005737	cytoplasm	DHRS2	IDA		Human	PMID:11944995
Cellular Component	GO:0005737	cytoplasm	DHRS2	IDA		Human	PMID:11997086
Cellular Component	GO:0005739	mitochondrion	DHRS2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	DHRS2	IDA		Human	PMID:19443906
Cellular Component	GO:0005635	nuclear envelope	DHRS2	IDA		Human	PMID:11997086
Cellular Component	GO:0005654	nucleoplasm	DHRS2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	DHRS2	IDA		Human	PMID:1847869
Biological Process	GO:0034599	cellular response to oxidative stress	DHRS2	IDA		Human	PMID:19443906
Biological Process	GO:0022900	electron transport chain	DHRS2	IDA		Human	PMID:16685466
Biological Process	GO:0043011	myeloid dendritic cell differentiation	DHRS2	IEP		Human	PMID:11944995
Biological Process	GO:0043066	negative regulation of apoptotic process	DHRS2	IMP		Human	PMID:19443906
Biological Process	GO:0009636	response to toxic substance	DHRS2	IDA		Human	PMID:16685466

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern