Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DGKH
  • Mouse genes Dgkh
  • Rat genes Dgkh
  • Zfish genes dgkh,si:dkey-172j4.3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dgkh

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004143	diacylglycerol kinase activity	DGKH	IMP		Human	PMID:12810723
Molecular Function	GO:0004143	diacylglycerol kinase activity	DGKH	IDA		Human	PMID:23949095
Molecular Function	GO:0004143	diacylglycerol kinase activity	Dgkh	IDA		Mouse	MGI:MGI:6253974|PMID:27643686
Cellular Component	GO:0015629	actin cytoskeleton	Dgkh	IDA		Mouse	MGI:MGI:6253974|PMID:27643686
Cellular Component	GO:0005737	cytoplasm	DGKH	IDA		Human	PMID:12810723
Cellular Component	GO:0005737	cytoplasm	Dgkh	IDA		Mouse	MGI:MGI:6253974|PMID:27643686
Cellular Component	GO:0005768	endosome	DGKH	IDA		Human	PMID:12810723
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	DGKH	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	DGKH	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Dgkh	IDA		Mouse	MGI:MGI:6253974|PMID:27643686
Biological Process	GO:0046339	diacylglycerol metabolic process	Dgkh	IDA		Mouse	MGI:MGI:6253974|PMID:27643686
Biological Process	GO:0046834	lipid phosphorylation	Dgkh	IDA		Mouse	MGI:MGI:6253974|PMID:27643686
Biological Process	GO:0006654	phosphatidic acid biosynthetic process	Dgkh	IDA		Mouse	MGI:MGI:6253974|PMID:27643686
Biological Process	GO:0046473	phosphatidic acid metabolic process	DGKH	IDA		Human	PMID:23949095
Biological Process	GO:0007205	protein kinase C-activating G protein-coupled receptor signaling pathway	DGKH	IMP		Human	PMID:12810723

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern