Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DEPTOR
  • Mouse genes Deptor
  • Rat genes Deptor
  • Zfish genes deptor
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Deptor

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	DEPTOR	IPI	UniProtKB:P42345	Human	PMID:19446321
Molecular Function	GO:0005515	protein binding	DEPTOR	IPI	UniProtKB:P42346	Human	PMID:19446321
Molecular Function	GO:0005515	protein binding	DEPTOR	IPI	UniProtKB:Q13077	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	DEPTOR	IPI	UniProtKB:Q8TBZ0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	DEPTOR	IPI	UniProtKB:Q9UPX6	Human	PMID:30080879
Molecular Function	GO:0005515	protein binding	DEPTOR	IPI	UniProtKB:Q9Y2K2	Human	PMID:30232230
Molecular Function	GO:0005515	protein binding	DEPTOR	IPI	UniProtKB:X5D778	Human	PMID:32296183
Biological Process	GO:0045792	negative regulation of cell size	DEPTOR	IMP		Human	PMID:19446321
Biological Process	GO:0006469	negative regulation of protein kinase activity	DEPTOR	IMP		Human	PMID:19446321
Biological Process	GO:0032007	negative regulation of TOR signaling	DEPTOR	IMP		Human	PMID:19446321
Biological Process	GO:1904262	negative regulation of TORC1 signaling	DEPTOR	IGI	UniProtKB:Q96G74	Human	PMID:33110214
Biological Process	GO:1903940	negative regulation of TORC2 signaling	DEPTOR	IGI	UniProtKB:Q96G74	Human	PMID:33110214
Biological Process	GO:2001236	regulation of extrinsic apoptotic signaling pathway	DEPTOR	IMP		Human	PMID:19446321

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern