Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DDX21
  • Mouse genes Ddx21
  • Rat genes Ddx21
  • Zfish genes ddx21
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ddx21

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0097322	7SK snRNA binding	DDX21	IDA		Human	PMID:25470060
Molecular Function	GO:0003725	double-stranded RNA binding	Ddx21	IDA		Mouse	PMID:21703541
Molecular Function	GO:0042802	identical protein binding	Ddx21	IDA		Mouse	MGI:MGI:5050760|PMID:21703541
Molecular Function	GO:0035198	miRNA binding	DDX21	IDA		Human	PMID:28431233
Molecular Function	GO:0005515	protein binding	DDX21	IPI	UniProtKB:P07910	Human	PMID:15034300
Molecular Function	GO:0005515	protein binding	DDX21	IPI	UniProtKB:Q15554	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	DDX21	IPI	UniProtKB:O60318	Human	PMID:23652018
Molecular Function	GO:0005515	protein binding	DDX21	IPI	UniProtKB:O00505	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	DDX21	IPI	UniProtKB:Q92793	Human	PMID:28790157
Molecular Function	GO:0005515	protein binding	DDX21	IPI	UniProtKB:Q9NRC8	Human	PMID:28790157
Molecular Function	GO:0005515	protein binding	DDX21	IPI	UniProtKB:P07910	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	DDX21	IPI	UniProtKB:P0DTC9	Human	PMID:32353859
Molecular Function	GO:0005515	protein binding	DDX21	IPI	UniProtKB:P10636	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DDX21	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DDX21	IPI	UniProtKB:Q8N187	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DDX21	IPI	UniProtKB:Q99732	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DDX21	IPI	UniProtKB:P0DTC9	Human	PMID:33060197
Molecular Function	GO:0005515	protein binding	DDX21	IPI	UniProtKB:P0DTC9	Human	PMID:34029587
Molecular Function	GO:0005515	protein binding	DDX21	IPI	UniProtKB:P0DTC9	Human	PMID:34232536
Molecular Function	GO:0005515	protein binding	DDX21	IPI	UniProtKB:O00505	Human	PMID:34564892
Molecular Function	GO:0005515	protein binding	DDX21	IPI	UniProtKB:P0DTC9	Human	PMID:34901782
Molecular Function	GO:0005515	protein binding	DDX21	IPI	UniProtKB:P0DTC9	Human	PMID:35107372
Molecular Function	GO:0005515	protein binding	Ddx21	IPI	UniProtKB:Q6ZQL4	Mouse	MGI:MGI:6323527|PMID:31128943
Molecular Function	GO:0005515	protein binding	Ddx21	IPI	PR:Q91VR5	Mouse	PMID:21703541
Molecular Function	GO:0005515	protein binding	Ddx21	IPI	PR:Q8VHK9	Mouse	PMID:21703541
Molecular Function	GO:0003723	RNA binding	DDX21	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	DDX21	HDA		Human	PMID:22681889
Molecular Function	GO:0003724	RNA helicase activity	DDX21	IMP		Human	PMID:25470060
Molecular Function	GO:0003724	RNA helicase activity	DDX21	IDA		Human	PMID:28790157
Molecular Function	GO:0003724	RNA helicase activity	DDX21	IDA		Human	PMID:9461305
Molecular Function	GO:0019843	rRNA binding	DDX21	IDA		Human	PMID:25470060
Molecular Function	GO:0030515	snoRNA binding	DDX21	IDA		Human	PMID:25470060
Cellular Component	GO:0110016	B-WICH complex	DDX21	IDA		Human	PMID:16603771
Cellular Component	GO:0005694	chromosome	DDX21	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Ddx21	IDA		Mouse	MGI:MGI:5050760|PMID:21703541
Cellular Component	GO:0016020	membrane	DDX21	HDA		Human	PMID:16210410
Cellular Component	GO:0016020	membrane	DDX21	HDA		Human	PMID:19946888
Cellular Component	GO:0005730	nucleolus	DDX21	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	DDX21	IDA		Human	PMID:28790157
Cellular Component	GO:0005654	nucleoplasm	DDX21	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	DDX21	IDA		Human	PMID:28790157
Biological Process	GO:0001649	osteoblast differentiation	DDX21	HDA		Human	PMID:16210410
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	Ddx21	IMP		Mouse	MGI:MGI:5050760|PMID:21703541
Biological Process	GO:0002735	positive regulation of myeloid dendritic cell cytokine production	Ddx21	IMP		Mouse	MGI:MGI:5050760|PMID:21703541
Biological Process	GO:0045945	positive regulation of transcription by RNA polymerase III	DDX21	IDA		Human	PMID:16603771
Biological Process	GO:0062176	R-loop processing	DDX21	IDA		Human	PMID:28790157
Biological Process	GO:0043330	response to exogenous dsRNA	Ddx21	IMP		Mouse	PMID:21703541
Biological Process	GO:0009615	response to virus	Ddx21	IMP		Mouse	PMID:21703541
Biological Process	GO:0006366	transcription by RNA polymerase II	DDX21	IMP		Human	PMID:25470060

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern