Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DDAH1
  • Mouse genes Ddah1
  • Rat genes Ddah1
  • Zfish genes ddah1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ddah1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016597	amino acid binding	Ddah1	IDA		Rat	PMID:17322279|RGD:1625578
Molecular Function	GO:0016403	dimethylargininase activity	DDAH1	IDA		Human	PMID:19663506
Molecular Function	GO:0016403	dimethylargininase activity	Ddah1	IMP		Mouse	MGI:MGI:5315329|PMID:21493890
Molecular Function	GO:0016403	dimethylargininase activity	Ddah1	IDA		Rat	PMID:12237779|RGD:727432
Molecular Function	GO:0016403	dimethylargininase activity	Ddah1	IDA		Rat	PMID:17322279|RGD:1625578
Cellular Component	GO:0070062	extracellular exosome	DDAH1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	DDAH1	HDA		Human	PMID:23533145
Cellular Component	GO:0005739	mitochondrion	Ddah1	HDA		Mouse	PMID:18614015
Biological Process	GO:0006527	arginine catabolic process	DDAH1	IDA		Human	PMID:24895913
Biological Process	GO:0006525	arginine metabolic process	Ddah1	IDA		Rat	PMID:17322279|RGD:1625578
Biological Process	GO:0000052	citrulline metabolic process	DDAH1	IDA		Human	PMID:19663506
Biological Process	GO:0008285	negative regulation of cell population proliferation	DDAH1	IDA		Human	PMID:24895913
Biological Process	GO:1900038	negative regulation of cellular response to hypoxia	DDAH1	IDA		Human	PMID:24895913
Biological Process	GO:0043116	negative regulation of vascular permeability	DDAH1	IDA		Human	PMID:24895913
Biological Process	GO:0045766	positive regulation of angiogenesis	Ddah1	IMP		Rat	PMID:12237779|RGD:727432
Biological Process	GO:0045429	positive regulation of nitric oxide biosynthetic process	Ddah1	IMP		Mouse	MGI:MGI:5315329|PMID:21493890
Biological Process	GO:0045429	positive regulation of nitric oxide biosynthetic process	Ddah1	IMP		Rat	PMID:12237779|RGD:727432
Biological Process	GO:0003073	regulation of systemic arterial blood pressure	Ddah1	IMP		Mouse	MGI:MGI:5315329|PMID:21493890

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern