Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DACT2
  • Mouse genes Dact2
  • Rat genes Dact2
  • Zfish genes dact2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dact2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008013	beta-catenin binding	Dact2	IDA		Mouse	MGI:MGI:5437409|PMID:21718540
Molecular Function	GO:0070097	delta-catenin binding	Dact2	IDA		Mouse	MGI:MGI:5437409|PMID:21718540
Molecular Function	GO:0005515	protein binding	Dact2	IPI	UniProtKB:Q0PHV7	Mouse	MGI:MGI:5437409|PMID:21718540
Molecular Function	GO:0005515	protein binding	dact2	IPI	UniProtKB:P36897	Zfish	PMID:15459392
Molecular Function	GO:0051018	protein kinase A binding	Dact2	IDA		Mouse	MGI:MGI:5437409|PMID:21718540
Molecular Function	GO:0005080	protein kinase C binding	Dact2	IDA		Mouse	MGI:MGI:5437409|PMID:21718540
Molecular Function	GO:0008134	transcription factor binding	Dact2	IDA		Mouse	MGI:MGI:5437409|PMID:21718540
Cellular Component	GO:0005739	mitochondrion	Dact2	HDA		Mouse	PMID:18614015
Biological Process	GO:0003382	epithelial cell morphogenesis	Dact2	IMP		Mouse	MGI:MGI:4833906|PMID:20685821
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	Dact2	IGI	MGI:MGI:1343184	Mouse	PMID:24029230
Biological Process	GO:0072061	inner medullary collecting duct development	Dact2	IMP		Mouse	MGI:MGI:4833906|PMID:20685821
Biological Process	GO:0048332	mesoderm morphogenesis	dact2	IMP		Zfish	PMID:15459392
Biological Process	GO:0007162	negative regulation of cell adhesion	Dact2	IMP		Mouse	MGI:MGI:3809364|PMID:18716284
Biological Process	GO:1900108	negative regulation of nodal signaling pathway	Dact2	IMP		Mouse	MGI:MGI:3809364|PMID:18716284
Biological Process	GO:1900108	negative regulation of nodal signaling pathway	Dact2	IDA		Mouse	MGI:MGI:5437437|PMID:17197390
Biological Process	GO:1900108	negative regulation of nodal signaling pathway	dact2	IDA		Zfish	PMID:15459392|ZFIN:ZDB-PUB-041006-8
Biological Process	GO:0043588	skin development	Dact2	IMP		Mouse	MGI:MGI:3809364|PMID:18716284
Biological Process	GO:0016055	Wnt signaling pathway	dact2	IMP		Zfish	PMID:15539487

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern