Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DACT1
  • Mouse genes Dact1
  • Rat genes Dact1
  • Zfish genes dact1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dact1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008013	beta-catenin binding	DACT1	IDA		Human	PMID:18936100
Molecular Function	GO:0008013	beta-catenin binding	DACT1	IPI	UniProtKB:P35222	Human	PMID:18936100
Molecular Function	GO:0008013	beta-catenin binding	DACT1	IDA		Human	PMID:22470507
Molecular Function	GO:0070097	delta-catenin binding	Dact1	IDA		Mouse	MGI:MGI:5437409|PMID:21718540
Molecular Function	GO:0042826	histone deacetylase binding	DACT1	IPI	UniProtKB:Q13547	Human	PMID:18936100
Molecular Function	GO:0005515	protein binding	DACT1	IPI	UniProtKB:O14641	Human	PMID:16446366
Molecular Function	GO:0005515	protein binding	DACT1	IPI	UniProtKB:O14641	Human	PMID:21262972
Molecular Function	GO:0005515	protein binding	DACT1	IPI	UniProtKB:P31946	Human	PMID:21262972
Molecular Function	GO:0005515	protein binding	DACT1	IPI	UniProtKB:P35222	Human	PMID:22470507
Molecular Function	GO:0005515	protein binding	DACT1	IPI	UniProtKB:P49841	Human	PMID:22470507
Molecular Function	GO:0005515	protein binding	DACT1	IPI	UniProtKB:O14641	Human	PMID:22610794
Molecular Function	GO:0005515	protein binding	DACT1	IPI	UniProtKB:Q9ULK5	Human	PMID:22610794
Molecular Function	GO:0005515	protein binding	Dact1	IPI	UniProtKB:P51141	Mouse	MGI:MGI:5284805|PMID:14636582
Molecular Function	GO:0005515	protein binding	Dact1	IPI	UniProtKB:P51141	Mouse	MGI:MGI:5009367|PMID:19637179
Molecular Function	GO:0005515	protein binding	Dact1	IPI	UniProtKB:P51141|UniProtKB:Q0PHV7|UniProtKB:Q60838|UniProtKB:Q91ZD4	Mouse	MGI:MGI:5437409|PMID:21718540
Molecular Function	GO:0005515	protein binding	Dact1	IPI	UniProtKB:P51142	Mouse	MGI:MGI:2447631|PMID:11970895
Molecular Function	GO:0005515	protein binding	Dact1	IPI	PR:Q91ZD4	Mouse	PMID:19701191
Molecular Function	GO:0051018	protein kinase A binding	DACT1	IDA		Human	PMID:21262972
Molecular Function	GO:0051018	protein kinase A binding	Dact1	IDA		Mouse	MGI:MGI:5437409|PMID:21718540
Molecular Function	GO:0005080	protein kinase C binding	Dact1	IDA		Mouse	MGI:MGI:5437409|PMID:21718540
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	DACT1	IPI	UniProtKB:Q9UJU2	Human	PMID:18936100
Cellular Component	GO:0005737	cytoplasm	DACT1	IDA		Human	PMID:16446366
Cellular Component	GO:0005737	cytoplasm	DACT1	IDA		Human	PMID:18936100
Cellular Component	GO:0005737	cytoplasm	DACT1	IDA		Human	PMID:22610794
Cellular Component	GO:0098978	glutamatergic synapse	Dact1	IDA		Mouse	PMID:23826333
Cellular Component	GO:0098978	glutamatergic synapse	Dact1	IMP		Mouse	PMID:23826333
Cellular Component	GO:0098978	glutamatergic synapse	Dact1	IDA		Mouse	PMID:20335472
Cellular Component	GO:0098978	glutamatergic synapse	Dact1	IEP		Mouse	PMID:20335472
Cellular Component	GO:0098978	glutamatergic synapse	Dact1	IMP		Mouse	PMID:20335472
Cellular Component	GO:0005654	nucleoplasm	DACT1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	DACT1	IDA		Human	PMID:18936100
Cellular Component	GO:0098794	postsynapse	Dact1	IDA		Mouse	PMID:20335472
Cellular Component	GO:0098794	postsynapse	Dact1	IEP		Mouse	PMID:20335472
Biological Process	GO:0048813	dendrite morphogenesis	Dact1	IGI	MGI:MGI:97845	Mouse	PMID:20335472
Biological Process	GO:0048813	dendrite morphogenesis	Dact1	IMP	MGI:MGI:4360072	Mouse	PMID:20335472
Biological Process	GO:0048619	embryonic hindgut morphogenesis	Dact1	IMP		Mouse	MGI:MGI:4457465|PMID:20145239
Biological Process	GO:0048598	embryonic morphogenesis	Dact1	IMP	MGI:MGI:4360072	Mouse	PMID:19701191
Biological Process	GO:0001702	gastrulation with mouth forming second	Dact1	IMP	MGI:MGI:4360072	Mouse	PMID:19701191
Biological Process	GO:1904864	negative regulation of beta-catenin-TCF complex assembly	DACT1	IDA		Human	PMID:18936100
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	DACT1	IGI	UniProtKB:P04426	Human	PMID:18936100
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	DACT1	IMP		Human	PMID:22610794
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	Dact1	IMP		Mouse	PMID:19073771
Biological Process	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	DACT1	IDA		Human	PMID:18936100
Biological Process	GO:0046329	negative regulation of JNK cascade	DACT1	IDA		Human	PMID:17197390
Biological Process	GO:0046329	negative regulation of JNK cascade	Dact1	IDA		Mouse	MGI:MGI:5437437|PMID:17197390
Biological Process	GO:0032091	negative regulation of protein binding	DACT1	IGI	UniProtKB:P35222,UniProtKB:Q9UJU2	Human	PMID:18936100
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	DACT1	IDA		Human	PMID:18936100
Biological Process	GO:0030178	negative regulation of Wnt signaling pathway	DACT1	IGI	UniProtKB:O14641	Human	PMID:16446366
Biological Process	GO:0030178	negative regulation of Wnt signaling pathway	DACT1	IDA		Human	PMID:16446366
Biological Process	GO:0030178	negative regulation of Wnt signaling pathway	DACT1	IDA		Human	PMID:17197390
Biological Process	GO:0030178	negative regulation of Wnt signaling pathway	DACT1	IMP		Human	PMID:18936100
Biological Process	GO:0030178	negative regulation of Wnt signaling pathway	Dact1	IDA		Mouse	MGI:MGI:5437437|PMID:17197390
Biological Process	GO:0021915	neural tube development	DACT1	IMP		Human	PMID:22610794
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	DACT1	IMP		Human	PMID:15580286
Biological Process	GO:0045600	positive regulation of fat cell differentiation	Dact1	IMP		Mouse	PMID:19073771
Biological Process	GO:0032092	positive regulation of protein binding	DACT1	IGI	UniProtKB:Q13547,UniProtKB:Q9UJU2	Human	PMID:18936100
Biological Process	GO:0045732	positive regulation of protein catabolic process	DACT1	IDA		Human	PMID:16446366
Biological Process	GO:0045732	positive regulation of protein catabolic process	DACT1	IMP		Human	PMID:18936100
Biological Process	GO:0030177	positive regulation of Wnt signaling pathway	DACT1	IDA		Human	PMID:21262972
Biological Process	GO:0060828	regulation of canonical Wnt signaling pathway	DACT1	IMP		Human	PMID:18936100
Biological Process	GO:0099175	regulation of postsynapse organization	Dact1	IDA		Mouse	PMID:23826333
Biological Process	GO:0099175	regulation of postsynapse organization	Dact1	IMP		Mouse	PMID:23826333
Biological Process	GO:0099175	regulation of postsynapse organization	Dact1	IDA		Mouse	PMID:20335472
Biological Process	GO:0099175	regulation of postsynapse organization	Dact1	IMP		Mouse	PMID:20335472
Biological Process	GO:0031647	regulation of protein stability	DACT1	IDA		Human	PMID:21262972
Biological Process	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway	Dact1	IMP		Mouse	MGI:MGI:4457465|PMID:20145239
Biological Process	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway	Dact1	IGI	MGI:MGI:2135272	Mouse	PMID:19701191
Biological Process	GO:0050808	synapse organization	Dact1	IMP	MGI:MGI:4360072	Mouse	PMID:20335472
Biological Process	GO:0016055	Wnt signaling pathway	dact1	IMP		Zfish	PMID:15539487

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern