Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KIAA0319
  • Mouse genes D130043K22Rik
  • Rat genes RGD1307443
  • Zfish genes kiaa0319
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set D130043K22Rik

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	KIAA0319	IPI	UniProtKB:Q96CW1	Human	PMID:19419997
Cellular Component	GO:0005769	early endosome	KIAA0319	IDA		Human	PMID:19419997
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	KIAA0319	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	KIAA0319	IDA		Human	PMID:19419997
Biological Process	GO:0033555	multicellular organismal response to stress	D130043K22Rik	IMP	MGI:MGI:5696928	Mouse	PMID:27510895
Biological Process	GO:0030517	negative regulation of axon extension	KIAA0319	IMP		Human	PMID:28334068
Biological Process	GO:0048692	negative regulation of axon extension involved in regeneration	KIAA0319	IMP		Human	PMID:28334068
Biological Process	GO:0048692	negative regulation of axon extension involved in regeneration	D130043K22Rik	IMP	MGI:MGI:4362922	Mouse	PMID:28334068
Biological Process	GO:2000171	negative regulation of dendrite development	KIAA0319	IGI		Human	PMID:19679544
Biological Process	GO:0001764	neuron migration	KIAA0319	IGI		Human	PMID:19679544
Biological Process	GO:0060391	positive regulation of SMAD protein signal transduction	KIAA0319	IGI	UniProtKB:O60674	Human	PMID:28334068
Biological Process	GO:0060391	positive regulation of SMAD protein signal transduction	KIAA0319	IGI	UniProtKB:Q9NRF2	Human	PMID:28334068
Biological Process	GO:0060391	positive regulation of SMAD protein signal transduction	KIAA0319	IMP		Human	PMID:28334068
Biological Process	GO:0010996	response to auditory stimulus	D130043K22Rik	IGI	MGI:MGI:2140475	Mouse	PMID:29045729

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern