Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CYTH4
  • Mouse genes Cyth4
  • Rat genes Cyth4
  • Zfish genes cyth4a,cyth4b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cyth4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	CYTH4	IDA		Human	PMID:10652308
Molecular Function	GO:0005515	protein binding	CYTH4	IPI	UniProtKB:Q969H4	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CYTH4	IPI	UniProtKB:O76011	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYTH4	IPI	UniProtKB:P08779	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYTH4	IPI	UniProtKB:P20618	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYTH4	IPI	UniProtKB:P53539	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYTH4	IPI	UniProtKB:P78358	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYTH4	IPI	UniProtKB:Q15154-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYTH4	IPI	UniProtKB:Q16204	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYTH4	IPI	UniProtKB:Q4G0X9-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYTH4	IPI	UniProtKB:Q63ZY3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYTH4	IPI	UniProtKB:Q86T90	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYTH4	IPI	UniProtKB:Q8N6Y0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYTH4	IPI	UniProtKB:Q8NA61-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYTH4	IPI	UniProtKB:Q8NCU1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYTH4	IPI	UniProtKB:Q8WWN9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYTH4	IPI	UniProtKB:Q969H4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYTH4	IPI	UniProtKB:Q96ED9-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYTH4	IPI	UniProtKB:Q96HB5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYTH4	IPI	UniProtKB:Q9UHG0	Human	PMID:32296183
Cellular Component	GO:0034451	centriolar satellite	CYTH4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	CYTH4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0045171	intercellular bridge	CYTH4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	CYTH4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	CYTH4	IDA		Human	PMID:17398095
Biological Process	GO:0055113	epiboly involved in gastrulation with mouth forming second	cyth4a	IGI	ZFIN:ZDB-GENE-030131-4311,ZFIN:ZDB-GENE-030131-657,ZFIN:ZDB-GENE-120612-1	Zfish	PMID:28736167

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern