Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CYRIB
  • Mouse genes Cyrib
  • Rat genes Cyrib
  • Zfish genes fam49ba,fam49bb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cyrib

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0023030	MHC class Ib protein binding, via antigen binding groove	Cyrib	IDA		Mouse	MGI:MGI:5432330|PMID:22522492
Molecular Function	GO:0005515	protein binding	CYRIB	IPI	UniProtKB:Q9GZT8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CYRIB	IPI	UniProtKB:O00291	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYRIB	IPI	UniProtKB:O14901	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CYRIB	IPI	UniProtKB:P46379-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Cyrib	IPI	PR:E9Q9D5	Mouse	PMID:23055941
Molecular Function	GO:0031267	small GTPase binding	CYRIB	IPI	UniProtKB:P63000	Human	PMID:30250061
Molecular Function	GO:0031267	small GTPase binding	CYRIB	IPI	UniProtKB:P63000	Human	PMID:31285585
Cellular Component	GO:0005929	cilium	Cyrib	IDA		Mouse	PMID:22326026
Cellular Component	GO:0070062	extracellular exosome	CYRIB	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	CYRIB	HDA		Human	PMID:20458337
Cellular Component	GO:0005739	mitochondrion	CYRIB	IDA		Human	PMID:29059164
Biological Process	GO:0071219	cellular response to molecule of bacterial origin	CYRIB	IMP		Human	PMID:31285585
Biological Process	GO:0071219	cellular response to molecule of bacterial origin	Cyrib	IMP		Mouse	MGI:MGI:6383257|PMID:31285585
Biological Process	GO:0030837	negative regulation of actin filament polymerization	CYRIB	IMP		Human	PMID:30250061
Biological Process	GO:0051058	negative regulation of small GTPase mediated signal transduction	CYRIB	IMP		Human	PMID:30250061
Biological Process	GO:0051058	negative regulation of small GTPase mediated signal transduction	CYRIB	IMP		Human	PMID:31285585
Biological Process	GO:0051058	negative regulation of small GTPase mediated signal transduction	Cyrib	IMP		Mouse	MGI:MGI:6383257|PMID:31285585
Biological Process	GO:2000568	positive regulation of memory T cell activation	Cyrib	IDA		Mouse	MGI:MGI:5432330|PMID:22522492
Biological Process	GO:0050870	positive regulation of T cell activation	Cyrib	IDA		Mouse	MGI:MGI:5432330|PMID:22522492
Biological Process	GO:0001916	positive regulation of T cell mediated cytotoxicity	Cyrib	IDA		Mouse	MGI:MGI:5432330|PMID:22522492
Biological Process	GO:0032729	positive regulation of type II interferon production	Cyrib	IDA		Mouse	MGI:MGI:5432330|PMID:22522492
Biological Process	GO:0030334	regulation of cell migration	CYRIB	IMP		Human	PMID:30250061
Biological Process	GO:0050920	regulation of chemotaxis	CYRIB	IMP		Human	PMID:30250061
Biological Process	GO:2000114	regulation of establishment of cell polarity	CYRIB	IMP		Human	PMID:30250061
Biological Process	GO:0090140	regulation of mitochondrial fission	CYRIB	IMP		Human	PMID:29059164
Biological Process	GO:0090140	regulation of mitochondrial fission	Cyrib	IMP		Mouse	MGI:MGI:6383355|PMID:29059164

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern