Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CYP7B1
  • Mouse genes Cyp7b1
  • Rat genes Cyp7b1
  • Zfish genes cyp7b1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cyp7b1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008396	oxysterol 7-alpha-hydroxylase activity	Cyp7b1	IMP		Mouse	MGI:MGI:5440118|PMID:22999953
Molecular Function	GO:0008396	oxysterol 7-alpha-hydroxylase activity	Cyp7b1	IDA		Mouse	MGI:MGI:1859119|PMID:10748047
Biological Process	GO:0035754	B cell chemotaxis	Cyp7b1	IMP		Mouse	MGI:MGI:5440118|PMID:22999953
Biological Process	GO:0006699	bile acid biosynthetic process	Cyp7b1	IDA		Mouse	MGI:MGI:1859119|PMID:10748047
Biological Process	GO:0007623	circadian rhythm	Cyp7b1	IDA		Rat	PMID:12759897|RGD:1298869
Biological Process	GO:0050673	epithelial cell proliferation	Cyp7b1	IMP	MGI:MGI:2182328	Mouse	PMID:12370428
Biological Process	GO:0030520	intracellular estrogen receptor signaling pathway	Cyp7b1	IMP	MGI:MGI:2182328	Mouse	PMID:12370428
Biological Process	GO:0007613	memory	Cyp7b1	IDA		Rat	PMID:17065445|RGD:1601037
Biological Process	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway	Cyp7b1	IMP	MGI:MGI:2182328	Mouse	PMID:12370428
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	Cyp7b1	IMP	MGI:MGI:2182328	Mouse	PMID:12370428
Biological Process	GO:0060740	prostate gland epithelium morphogenesis	Cyp7b1	IMP	MGI:MGI:2182328	Mouse	PMID:12370428
Biological Process	GO:0051591	response to cAMP	Cyp7b1	IEP		Rat	PMID:12029625|RGD:1298868
Biological Process	GO:0009410	response to xenobiotic stimulus	Cyp7b1	IEP		Rat	PMID:12029625|RGD:1298868

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern