Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CYP24A1
  • Mouse genes Cyp24a1
  • Rat genes Cyp24a1
  • Zfish genes cyp24a1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cyp24a1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0062181	1-alpha,25-dihydroxyvitamin D3 23-hydroxylase activity	CYP24A1	IDA		Human	PMID:16617161
Molecular Function	GO:0062181	1-alpha,25-dihydroxyvitamin D3 23-hydroxylase activity	CYP24A1	IDA		Human	PMID:24893882
Molecular Function	GO:0062181	1-alpha,25-dihydroxyvitamin D3 23-hydroxylase activity	CYP24A1	IDA		Human	PMID:29461981
Molecular Function	GO:0030342	1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity	CYP24A1	IDA		Human	PMID:16617161
Molecular Function	GO:0030342	1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity	CYP24A1	IDA		Human	PMID:24893882
Molecular Function	GO:0030342	1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity	CYP24A1	IDA		Human	PMID:8506296
Molecular Function	GO:0030342	1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity	CYP24A1	IDA		Human	PMID:8679605
Molecular Function	GO:0030342	1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity	Cyp24a1	IDA		Rat	PMID:10231362|RGD:14995316
Molecular Function	GO:0030342	1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity	Cyp24a1	IDA		Rat	PMID:16617161|RGD:14995311
Molecular Function	GO:0062180	25-hydroxycholecalciferol-23-hydroxylase activity	CYP24A1	IDA		Human	PMID:11012668
Molecular Function	GO:0062180	25-hydroxycholecalciferol-23-hydroxylase activity	CYP24A1	IDA		Human	PMID:24893882
Molecular Function	GO:0062180	25-hydroxycholecalciferol-23-hydroxylase activity	CYP24A1	IDA		Human	PMID:8679605
Molecular Function	GO:0008403	25-hydroxycholecalciferol-24-hydroxylase activity	CYP24A1	IDA		Human	PMID:24893882
Molecular Function	GO:0008403	25-hydroxycholecalciferol-24-hydroxylase activity	CYP24A1	IDA		Human	PMID:8679605
Molecular Function	GO:0008403	25-hydroxycholecalciferol-24-hydroxylase activity	Cyp24a1	IMP	MGI:MGI:2182338	Mouse	PMID:15225763
Molecular Function	GO:0008403	25-hydroxycholecalciferol-24-hydroxylase activity	Cyp24a1	IDA		Rat	PMID:10231362|RGD:14995316
Molecular Function	GO:0008403	25-hydroxycholecalciferol-24-hydroxylase activity	Cyp24a1	IDA		Rat	PMID:1991512|RGD:1298844
Molecular Function	GO:0070576	vitamin D 24-hydroxylase activity	Cyp24a1	IDA		Rat	PMID:25727742|RGD:14995325
Molecular Function	GO:0070643	vitamin D 25-hydroxylase activity	CYP24A1	IDA		Human	PMID:25727742
Molecular Function	GO:0070643	vitamin D 25-hydroxylase activity	Cyp24a1	IDA		Rat	PMID:25727742|RGD:14995325
Cellular Component	GO:0005739	mitochondrion	Cyp24a1	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Cyp24a1	HDA		Mouse	PMID:18614015
Biological Process	GO:0071305	cellular response to vitamin D	Cyp24a1	IEP		Rat	PMID:28104492|RGD:151665513
Biological Process	GO:0001649	osteoblast differentiation	CYP24A1	IEP		Human	PMID:17023519
Biological Process	GO:0033280	response to vitamin D	CYP24A1	IDA		Human	PMID:16720713
Biological Process	GO:0042369	vitamin D catabolic process	CYP24A1	IDA		Human	PMID:16617161
Biological Process	GO:0042369	vitamin D catabolic process	CYP24A1	IDA		Human	PMID:24893882
Biological Process	GO:0042369	vitamin D catabolic process	CYP24A1	IDA		Human	PMID:29461981
Biological Process	GO:0042369	vitamin D catabolic process	CYP24A1	IDA		Human	PMID:8506296
Biological Process	GO:0042369	vitamin D catabolic process	CYP24A1	IDA		Human	PMID:8679605
Biological Process	GO:0042369	vitamin D catabolic process	Cyp24a1	IDA		Rat	PMID:10231362|RGD:14995316
Biological Process	GO:0042369	vitamin D catabolic process	Cyp24a1	IDA		Rat	PMID:16617161|RGD:14995311
Biological Process	GO:0042359	vitamin D metabolic process	Cyp24a1	IMP	MGI:MGI:2182338	Mouse	PMID:15225763
Biological Process	GO:0042359	vitamin D metabolic process	Cyp24a1	IDA		Rat	PMID:1991512|RGD:1298844

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern