Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CYB561D2
  • Mouse genes Cyb561d2
  • Rat genes Cyb561d2
  • Zfish genes cyb561d2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cyb561d2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0020037	heme binding	CYB561D2	IDA		Human	PMID:19734123
Molecular Function	GO:0020037	heme binding	Cyb561d2	IDA		Mouse	MGI:MGI:6202493|PMID:19943161
Molecular Function	GO:0020037	heme binding	Cyb561d2	IMP		Mouse	MGI:MGI:6202479|PMID:17938141
Molecular Function	GO:0005515	protein binding	CYB561D2	IPI	UniProtKB:O15173	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB561D2	IPI	UniProtKB:O75208	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB561D2	IPI	UniProtKB:O95471	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB561D2	IPI	UniProtKB:P11912	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB561D2	IPI	UniProtKB:P27815-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB561D2	IPI	UniProtKB:P54219-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB561D2	IPI	UniProtKB:P54829	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB561D2	IPI	UniProtKB:Q3SXY8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB561D2	IPI	UniProtKB:Q5JX71	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB561D2	IPI	UniProtKB:Q6P9G4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB561D2	IPI	UniProtKB:Q86T13	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB561D2	IPI	UniProtKB:Q8TED1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB561D2	IPI	UniProtKB:Q96B21	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB561D2	IPI	UniProtKB:Q96BA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB561D2	IPI	UniProtKB:Q96TC7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB561D2	IPI	UniProtKB:Q9BRI3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB561D2	IPI	UniProtKB:Q9Y282	Human	PMID:32296183
Molecular Function	GO:0140571	transmembrane ascorbate ferrireductase activity	Cyb561d2	IMP		Mouse	MGI:MGI:6202479|PMID:17938141
Molecular Function	GO:0140575	transmembrane monodehydroascorbate reductase activity	CYB561D2	IDA		Human	PMID:23235316
Cellular Component	GO:0005783	endoplasmic reticulum	Cyb561d2	IDA		Mouse	MGI:MGI:6202479|PMID:17938141
Cellular Component	GO:0031982	vesicle	Cyb561d2	IDA		Mouse	MGI:MGI:6202479|PMID:17938141
Biological Process	GO:0140576	ascorbate homeostasis	CYB561D2	IDA		Human	PMID:23235316

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern