Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CUL5
  • Mouse genes Cul5
  • Rat genes Cul5
  • Zfish genes cul5a,cul5b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cul5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:Q86VP6	Human	PMID:12504025
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:Q8WXK4	Human	PMID:16325183
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:Q96Q27-2	Human	PMID:16325183
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:Q9H672	Human	PMID:16325183
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:Q9NWX5	Human	PMID:16325183
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:Q9Y576	Human	PMID:16325183
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:P42858	Human	PMID:17500595
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:P62877	Human	PMID:18805092
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:Q96GG9	Human	PMID:18826954
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:O41974	Human	PMID:19322197
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:P04626	Human	PMID:19933325
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:Q96Q27	Human	PMID:21119685
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:O14508	Human	PMID:21145461
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:Q9H672	Human	PMID:21145461
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:Q9NWX5	Human	PMID:21145461
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:Q9UBF6	Human	PMID:21145461
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:Q9Y576	Human	PMID:21145461
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:Q96A44	Human	PMID:21199876
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:Q96BD6	Human	PMID:21199876
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:Q99619	Human	PMID:21199876
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:Q9UBF6	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:Q86X83	Human	PMID:21778237
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:Q8N668	Human	PMID:21778237
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:Q9H0A8	Human	PMID:21778237
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:Q9NX08	Human	PMID:21778237
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:Q9UBI1	Human	PMID:21778237
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:P12504	Human	PMID:22190034
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:O95376	Human	PMID:24076655
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:P12504	Human	PMID:24402281
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:O95273	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:Q08379	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:Q9UBF6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:Q6PH85	Human	PMID:26906416
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:Q8IWE4	Human	PMID:26906416
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:Q92564	Human	PMID:26906416
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:Q96GG9	Human	PMID:26906416
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:Q9BTE7	Human	PMID:26906416
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:Q03468	Human	PMID:28292928
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:Q63187	Human	PMID:28292928
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:O14508	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:Q96Q27-2	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:Q9H672	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:Q9NWX5	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:Q9Y576	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:O14508	Human	PMID:29997244
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:O14508	Human	PMID:30833792
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:O95273	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:Q5T7N3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:Q9NPC3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:Q9UBF6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:Q9Y2V7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:O14508	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CUL5	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Cul5	IPI	PR:Q8VHQ2	Mouse	PMID:24210661
Molecular Function	GO:0005515	protein binding	Cul5	IPI	PR:O35718	Mouse	PMID:15601820
Molecular Function	GO:0005515	protein binding	Cul5	IPI	PR:Q9JLV5	Mouse	PMID:22709582
Molecular Function	GO:0005515	protein binding	Cul5	IPI	PR:E9Q9D5	Mouse	PMID:23055941
Molecular Function	GO:0031625	ubiquitin protein ligase binding	CUL5	IDA		Human	PMID:17636018
Cellular Component	GO:0031466	Cul5-RING ubiquitin ligase complex	CUL5	IDA		Human	PMID:17636018
Cellular Component	GO:0031466	Cul5-RING ubiquitin ligase complex	CUL5	IDA		Human	PMID:22405651
Cellular Component	GO:0005737	cytoplasm	Cul5	IDA		Rat	PMID:12821186|RGD:1299331
Cellular Component	GO:0005634	nucleus	Cul5	IDA		Rat	PMID:12821186|RGD:1299331
Cellular Component	GO:0005886	plasma membrane	Cul5	IDA		Rat	PMID:17950367|RGD:2301431
Cellular Component	GO:0090734	site of DNA damage	CUL5	IDA		Human	PMID:28292928
Biological Process	GO:0021799	cerebral cortex radially oriented cell migration	Cul5	IMP		Mouse	PMID:24210661
Biological Process	GO:0016567	protein ubiquitination	Cul5	IGI	MGI:MGI:2651588	Mouse	PMID:24210661
Biological Process	GO:0021942	radial glia guided migration of Purkinje cell	Cul5	IMP		Mouse	PMID:24210661
Biological Process	GO:0051480	regulation of cytosolic calcium ion concentration	Cul5	IMP		Rat	PMID:11409851|RGD:2301450
Biological Process	GO:0006970	response to osmotic stress	Cul5	IEP		Rat	PMID:12631466|RGD:1299332

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern