Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes COTL1
  • Mouse genes Cotl1
  • Rat genes Cotl1
  • Zfish genes cotl1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cotl1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	COTL1	IDA		Human	PMID:11583571
Molecular Function	GO:0003779	actin binding	Cotl1	IDA		Mouse	PMID:11785969
Molecular Function	GO:0019899	enzyme binding	COTL1	IPI	UniProtKB:P09917	Human	PMID:11297527
Molecular Function	GO:0019899	enzyme binding	Cotl1	IPI	UniProtKB:P09917	Mouse	MGI:MGI:2157200|PMID:11785969
Molecular Function	GO:0005515	protein binding	COTL1	IPI	UniProtKB:P09917	Human	PMID:11297527
Molecular Function	GO:0005515	protein binding	COTL1	IPI	UniProtKB:P09917	Human	PMID:16924104
Molecular Function	GO:0005515	protein binding	COTL1	IPI	UniProtKB:Q9NYB0	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	COTL1	IPI	UniProtKB:Q13956	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	Cotl1	IPI	UniProtKB:P09917	Mouse	PMID:11785969
Cellular Component	GO:0005829	cytosol	COTL1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	COTL1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	COTL1	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	COTL1	HDA		Human	PMID:23533145
Biological Process	GO:0050832	defense response to fungus	Cotl1	IDA		Mouse	MGI:MGI:2157200|PMID:11785969

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern