Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes COPS8
  • Mouse genes Cops8
  • Rat genes Cops8
  • Zfish genes cops8
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cops8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	COPS8	IPI	UniProtKB:Q9UNS2	Human	PMID:20399188
Molecular Function	GO:0005515	protein binding	COPS8	IPI	UniProtKB:Q13098-7	Human	PMID:25043011
Molecular Function	GO:0005515	protein binding	COPS8	IPI	UniProtKB:Q9UNS2	Human	PMID:25043011
Molecular Function	GO:0005515	protein binding	COPS8	IPI	UniProtKB:Q8N6Y0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	COPS8	IPI	UniProtKB:Q9UNS2	Human	PMID:27173435
Molecular Function	GO:0005515	protein binding	COPS8	IPI	UniProtKB:Q9UNS2	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	COPS8	IPI	UniProtKB:P51687	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	COPS8	IPI	UniProtKB:Q9UNS2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Cops8	IPI	PR:P61202	Mouse	PMID:9707402
Molecular Function	GO:0005515	protein binding	Cops8	IPI	PR:O88545	Mouse	PMID:9707402
Molecular Function	GO:0005515	protein binding	Cops8	IPI	PR:O88543	Mouse	PMID:9707402
Molecular Function	GO:0005515	protein binding	Cops8	IPI	PR:O35864	Mouse	PMID:9707402
Molecular Function	GO:0005515	protein binding	Cops8	IPI	PR:O88544	Mouse	PMID:9707402
Molecular Function	GO:0005515	protein binding	Cops8	IPI	PR:Q99LD4	Mouse	PMID:9707402
Cellular Component	GO:0008180	COP9 signalosome	COPS8	IPI		Human	PMID:25043011
Cellular Component	GO:0008180	COP9 signalosome	COPS8	IDA		Human	PMID:18850735
Cellular Component	GO:0008180	COP9 signalosome	COPS8	IDA		Human	PMID:9535219
Cellular Component	GO:0008180	COP9 signalosome	Cops8	IDA		Mouse	PMID:9707402
Cellular Component	GO:0005737	cytoplasm	COPS8	IDA		Human	PMID:24421388
Cellular Component	GO:0005829	cytosol	COPS8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	COPS8	HDA		Human	PMID:19056867
Cellular Component	GO:0005654	nucleoplasm	COPS8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	COPS8	IDA		Human	PMID:24421388
Cellular Component	GO:0005634	nucleus	Cops8	IDA		Mouse	PMID:14636993
Cellular Component	GO:0048471	perinuclear region of cytoplasm	COPS8	IDA		Human	PMID:9535219
Biological Process	GO:0007250	activation of NF-kappaB-inducing kinase activity	COPS8	IMP		Human	PMID:22992343
Biological Process	GO:0008285	negative regulation of cell population proliferation	COPS8	IMP		Human	PMID:23689509
Biological Process	GO:0000338	protein deneddylation	COPS8	IDA		Human	PMID:19141280
Biological Process	GO:0006468	protein phosphorylation	COPS8	IDA		Human	PMID:9535219

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern