Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes COL4A4
  • Mouse genes Col4a4
  • Rat genes Col4a4
  • Zfish genes col4a4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Col4a4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005201	extracellular matrix structural constituent	COL4A4	IMP		Human	PMID:17942953
Molecular Function	GO:0005201	extracellular matrix structural constituent	COL4A4	IMP		Human	PMID:19675380
Molecular Function	GO:0005201	extracellular matrix structural constituent	Col4a4	IPI	UniProtKB:P55268	Mouse	MGI:MGI:69166|PMID:7962065
Molecular Function	GO:0060090	molecular adaptor activity	COL4A4	EXP		Human	PMID:30443360
Cellular Component	GO:0005604	basement membrane	COL4A4	IDA		Human	PMID:2211832
Cellular Component	GO:0005604	basement membrane	Col4a4	IDA		Mouse	PMID:19275937
Cellular Component	GO:0005604	basement membrane	Col4a4	IDA		Mouse	PMID:11732842
Cellular Component	GO:0005604	basement membrane	Col4a4	IDA		Mouse	PMID:10534397
Cellular Component	GO:0005604	basement membrane	Col4a4	IDA		Mouse	PMID:9264260
Cellular Component	GO:0005587	collagen type IV trimer	COL4A4	IDA		Human	PMID:7523402
Cellular Component	GO:0005587	collagen type IV trimer	Col4a4	IDA		Mouse	MGI:MGI:69166|PMID:7962065
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL4A4	HDA		Human	PMID:25037231
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Col4a4	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Col4a4	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Biological Process	GO:0032836	glomerular basement membrane development	COL4A4	IMP		Human	PMID:17942953
Biological Process	GO:0032836	glomerular basement membrane development	COL4A4	IMP		Human	PMID:19675380
Biological Process	GO:0032836	glomerular basement membrane development	Col4a4	IMP	MGI:MGI:1857960	Mouse	PMID:10534397

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern