Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CLTA
  • Mouse genes Clta
  • Rat genes Clta
  • Zfish genes clta
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Clta

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0032050	clathrin heavy chain binding	CLTA	IPI	UniProtKB:Q00610	Human	PMID:4066749
Molecular Function	GO:0051020	GTPase binding	Clta	IPI	UniProtKB:O35303	Rat	PMID:23792689|RGD:12793033
Molecular Function	GO:0042277	peptide binding	Clta	IDA		Rat	PMID:1490999|RGD:2303177
Molecular Function	GO:0005515	protein binding	CLTA	IPI	UniProtKB:Q9NYX4	Human	PMID:16595675
Molecular Function	GO:0005515	protein binding	CLTA	IPI	UniProtKB:Q00610	Human	PMID:21297582
Molecular Function	GO:0005515	protein binding	CLTA	IPI	UniProtKB:Q9Y6A5	Human	PMID:21297582
Molecular Function	GO:0005515	protein binding	CLTA	IPI	UniProtKB:Q00610	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	Clta	IPI	UniProtKB:P49418	Rat	PMID:17762867|RGD:8554310
Molecular Function	GO:0005515	protein binding	Clta	IPI	UniProtKB:P53563	Rat	PMID:23792689|RGD:12793033
Molecular Function	GO:0005515	protein binding	Clta	IPI	UniProtKB:P53563-1	Rat	PMID:23792689|RGD:12793033
Molecular Function	GO:0044877	protein-containing complex binding	Clta	IPI	RGD:1310230|RGD:2200|RGD:620416	Rat	PMID:23792689|RGD:12793033
Cellular Component	GO:0030118	clathrin coat	CLTA	IMP		Human	PMID:11756460
Cellular Component	GO:0030118	clathrin coat	Clta	IDA		Rat	PMID:1490999|RGD:2303177
Cellular Component	GO:0030118	clathrin coat	Clta	IDA		Rat	PMID:17978091|RGD:2303184
Cellular Component	GO:0071439	clathrin complex	CLTA	IDA		Human	PMID:4066749
Cellular Component	GO:0005905	clathrin-coated pit	Clta	IDA		Rat	PMID:14985443|RGD:2301373
Cellular Component	GO:0030136	clathrin-coated vesicle	Clta	IDA		Rat	PMID:15933375|RGD:2301372
Cellular Component	GO:0031410	cytoplasmic vesicle	Clta	IDA		Mouse	MGI:MGI:5448522|PMID:20730103
Cellular Component	GO:0098978	glutamatergic synapse	Clta	IMP		Mouse	PMID:17880892
Cellular Component	GO:0098978	glutamatergic synapse	Clta	IDA		Mouse	PMID:17880892
Cellular Component	GO:0016020	membrane	CLTA	HDA		Human	PMID:19946888
Cellular Component	GO:0098843	postsynaptic endocytic zone	Clta	IMP		Mouse	PMID:17880892
Cellular Component	GO:0098843	postsynaptic endocytic zone	Clta	IDA		Mouse	PMID:17880892
Cellular Component	GO:0099631	postsynaptic endocytic zone cytoplasmic component	Clta	IDA		Mouse	MGI:MGI:5819350|PMID:17880892
Cellular Component	GO:0098835	presynaptic endocytic zone membrane	Clta	IDA		Rat	PMID:1325974|RGD:13702292
Cellular Component	GO:0030672	synaptic vesicle membrane	Clta	IDA		Rat	PMID:1325974|RGD:13702292
Cellular Component	GO:0030672	synaptic vesicle membrane	Clta	IDA		Rat	PMID:23792689|RGD:12793033
Biological Process	GO:0048268	clathrin coat assembly	CLTA	IMP		Human	PMID:11756460
Biological Process	GO:0006897	endocytosis	Clta	IEP		Rat	PMID:14985443|RGD:2301373

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern