Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CLIC5
  • Mouse genes Clic5
  • Rat genes Clic5
  • Zfish genes clic5a,clic5b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Clic5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005254	chloride channel activity	Clic5	IDA		Rat	PMID:8537381|RGD:727234
Molecular Function	GO:0005515	protein binding	CLIC5	IPI	UniProtKB:P15311	Human	PMID:10793131
Molecular Function	GO:0005515	protein binding	CLIC5	IPI	UniProtKB:P00523	Human	PMID:16831863
Cellular Component	GO:0015629	actin cytoskeleton	CLIC5	IDA		Human	PMID:10793131
Cellular Component	GO:0070062	extracellular exosome	CLIC5	HDA		Human	PMID:19056867
Cellular Component	GO:0032420	stereocilium	Clic5	IDA		Mouse	PMID:17021174
Cellular Component	GO:0032421	stereocilium bundle	Clic5	IDA		Rat	PMID:17021174|RGD:8554297
Biological Process	GO:0060088	auditory receptor cell stereocilium organization	Clic5	IMP	MGI:MGI:3663254	Mouse	PMID:17021174
Biological Process	GO:0006821	chloride transport	CLIC5	IDA		Human	PMID:10793131
Biological Process	GO:0002024	diet induced thermogenesis	Clic5	IMP	MGI:MGI:3663254	Mouse	PMID:20357015
Biological Process	GO:0050885	neuromuscular process controlling balance	Clic5	IMP	MGI:MGI:3663254	Mouse	PMID:17021174
Biological Process	GO:0008104	protein localization	Clic5	IMP	MGI:MGI:3663254	Mouse	PMID:17021174
Biological Process	GO:0002021	response to dietary excess	Clic5	IMP	MGI:MGI:3663254	Mouse	PMID:20357015
Biological Process	GO:0007605	sensory perception of sound	CLIC5	IMP		Human	PMID:24781754
Biological Process	GO:0007605	sensory perception of sound	Clic5	IMP	MGI:MGI:3663254	Mouse	PMID:17021174

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern