Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CKB
  • Mouse genes Ckb
  • Rat genes Ckb
  • Zfish genes ckba,ckbb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ckb

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004111	creatine kinase activity	Ckb	IDA		Mouse	PMID:33597756
Molecular Function	GO:0004111	creatine kinase activity	Ckb	IDA		Mouse	PMID:10481911
Molecular Function	GO:0005515	protein binding	CKB	IPI	UniProtKB:Q96DX5	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	CKB	IPI	UniProtKB:Q96DX5	Human	PMID:19060904
Molecular Function	GO:0005515	protein binding	CKB	IPI	UniProtKB:Q03463:PRO_0000278738	Human	PMID:19264780
Molecular Function	GO:0005515	protein binding	CKB	IPI	UniProtKB:Q96DX5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CKB	IPI	UniProtKB:Q96DX5	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CKB	IPI	UniProtKB:Q96DX5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Ckb	IPI	PR:Q91ZT8	Mouse	PMID:17148442
Molecular Function	GO:0005515	protein binding	Ckb	IPI	PR:E9Q9D5	Mouse	PMID:23055941
Molecular Function	GO:0005515	protein binding	Ckb	IPI	RGD:620811	Rat	PMID:15094054|RGD:1598444
Molecular Function	GO:0005515	protein binding	Ckb	IPI	RGD:620060	Rat	PMID:23142228|RGD:9686444
Molecular Function	GO:0031625	ubiquitin protein ligase binding	CKB	IPI	UniProtKB:O60260	Human	PMID:19725078
Cellular Component	GO:0005829	cytosol	CKB	IDA		Human	GO_REF:0000052
Cellular Component	GO:0030425	dendrite	Ckb	IDA		Rat	PMID:7517967|RGD:11565085
Cellular Component	GO:0070062	extracellular exosome	CKB	HDA		Human	PMID:11487543
Cellular Component	GO:0070062	extracellular exosome	CKB	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	CKB	HDA		Human	PMID:23533145
Cellular Component	GO:0005739	mitochondrion	Ckb	IDA		Mouse	PMID:33597756
Cellular Component	GO:0005739	mitochondrion	Ckb	HDA		Mouse	PMID:14651853
Cellular Component	GO:0043209	myelin sheath	Ckb	HDA		Mouse	MGI:MGI:3834050|PMID:17634366
Cellular Component	GO:0043025	neuronal cell body	Ckb	IDA		Rat	PMID:7517967|RGD:11565085
Cellular Component	GO:0005634	nucleus	Ckb	IDA		Rat	PMID:8847407|RGD:11565084
Biological Process	GO:0007420	brain development	Ckb	IEP		Rat	PMID:8847407|RGD:11565084
Biological Process	GO:0071391	cellular response to estrogen stimulus	Ckb	IEP		Rat	PMID:17272396|RGD:152177689
Biological Process	GO:1904568	cellular response to wortmannin	Ckb	IEP		Rat	PMID:17272396|RGD:152177689
Biological Process	GO:0021549	cerebellum development	Ckb	IEP		Rat	PMID:12093362|RGD:625711
Biological Process	GO:0140651	futile creatine cycle	Ckb	IDA		Mouse	PMID:33597756
Biological Process	GO:0030644	intracellular chloride ion homeostasis	Ckb	IMP		Rat	PMID:16336223|RGD:1598443
Biological Process	GO:0021762	substantia nigra development	CKB	HEP		Human	PMID:22926577

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern