Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CISH
  • Mouse genes Cish
  • Rat genes Cish
  • Zfish genes cish,cishb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cish

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	CISH	IPI	UniProtKB:P00533	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	CISH	IPI	UniProtKB:P04626	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	CISH	IPI	UniProtKB:P00533	Human	PMID:24658140
Molecular Function	GO:0005515	protein binding	CISH	IPI	UniProtKB:P00533	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	CISH	IPI	UniProtKB:O14773	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CISH	IPI	UniProtKB:P50570-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CISH	IPI	UniProtKB:P54253	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CISH	IPI	UniProtKB:Q8N187	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Cish	IPI	UniProtKB:P19235	Mouse	MGI:MGI:3688360|PMID:15644415
Molecular Function	GO:0005515	protein binding	Cish	IPI	UniProtKB:P19235	Mouse	MGI:MGI:3688025|PMID:11781573
Molecular Function	GO:0005515	protein binding	Cish	IPI	PR:P20444	Mouse	PMID:12618484
Cellular Component	GO:0005886	plasma membrane	Cish	IDA		Mouse	PMID:12618484
Biological Process	GO:0019221	cytokine-mediated signaling pathway	Cish	IEP		Rat	PMID:10579313|RGD:724748
Biological Process	GO:0045647	negative regulation of erythrocyte differentiation	cish	IMP	ZFIN:ZDB-MRPHLNO-151021-8	Zfish	PMID:24835394
Biological Process	GO:1903707	negative regulation of hemopoiesis	cish	IMP	ZFIN:ZDB-MRPHLNO-151021-8	Zfish	PMID:24835394
Biological Process	GO:0045620	negative regulation of lymphocyte differentiation	cish	IMP	ZFIN:ZDB-MRPHLNO-151021-8	Zfish	PMID:24835394
Biological Process	GO:0045638	negative regulation of myeloid cell differentiation	cish	IMP	ZFIN:ZDB-MRPHLNO-151021-8	Zfish	PMID:24835394
Biological Process	GO:0046426	negative regulation of receptor signaling pathway via JAK-STAT	cish	IMP	ZFIN:ZDB-MRPHLNO-151021-8	Zfish	PMID:24835394
Biological Process	GO:0007205	protein kinase C-activating G protein-coupled receptor signaling pathway	Cish	IDA		Mouse	PMID:12618484

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern