Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CHML
  • Mouse genes Chml
  • Rat genes
  • Zfish genes chm
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Chml

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004663	Rab geranylgeranyltransferase activity	chm	IMP	ZFIN:ZDB-GENO-090828-3	Zfish	PMID:19117920
Molecular Function	GO:0031267	small GTPase binding	CHML	IDA		Human	PMID:15186776
Molecular Function	GO:0031267	small GTPase binding	CHML	IPI	UniProtKB:P51159	Human	PMID:15186776
Molecular Function	GO:0031267	small GTPase binding	CHML	IPI	UniProtKB:P62820	Human	PMID:15186776
Cellular Component	GO:0005829	cytosol	CHML	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	CHML	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005968	Rab-protein geranylgeranyltransferase complex	CHML	IMP		Human	PMID:12356470
Biological Process	GO:0008203	cholesterol metabolic process	chm	IMP	ZFIN:ZDB-GENO-221017-2	Zfish	PMID:33755601
Biological Process	GO:0048058	compound eye corneal lens development	chm	IMP	ZFIN:ZDB-GENO-221017-2	Zfish	PMID:33755601
Biological Process	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound	chm	IMP		Zfish	PMID:14983050
Biological Process	GO:0042491	inner ear auditory receptor cell differentiation	chm	IMP	ZFIN:ZDB-GENO-090828-3	Zfish	PMID:14983050
Biological Process	GO:0050935	iridophore differentiation	chm	IMP	ZFIN:ZDB-GENO-090828-3	Zfish	PMID:14983050
Biological Process	GO:0098727	maintenance of cell number	chm	IMP	ZFIN:ZDB-GENO-170308-1	Zfish	PMID:28055019
Biological Process	GO:0043066	negative regulation of apoptotic process	chm	IMP	ZFIN:ZDB-GENO-170427-2	Zfish	PMID:28230863
Biological Process	GO:0018344	protein geranylgeranylation	CHML	IMP		Human	PMID:12356470
Biological Process	GO:0018344	protein geranylgeranylation	CHML	IDA		Human	PMID:15186776
Biological Process	GO:0001895	retina homeostasis	chm	IMP	ZFIN:ZDB-GENO-090828-3	Zfish	PMID:27329764
Biological Process	GO:0010842	retina layer formation	chm	IMP	ZFIN:ZDB-GENO-221017-2	Zfish	PMID:33755601
Biological Process	GO:0010842	retina layer formation	chm	IMP	ZFIN:ZDB-GENO-090828-3	Zfish	PMID:27329764
Biological Process	GO:0060042	retina morphogenesis in camera-type eye	chm	IMP	ZFIN:ZDB-GENO-090828-3	Zfish	PMID:19117920
Biological Process	GO:0060042	retina morphogenesis in camera-type eye	chm	IMP	ZFIN:ZDB-GENO-090828-3	Zfish	PMID:17360570
Biological Process	GO:0048798	swim bladder inflation	chm	IMP	ZFIN:ZDB-GENO-090828-3	Zfish	PMID:18809619

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern