Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CH25H
  • Mouse genes Ch25h
  • Rat genes Ch25h
  • Zfish genes ch25h
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ch25h

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001567	cholesterol 25-hydroxylase activity	CH25H	IDA		Human	PMID:32944968
Molecular Function	GO:0001567	cholesterol 25-hydroxylase activity	Ch25h	IDA		Mouse	MGI:MGI:6101070|PMID:29033131
Molecular Function	GO:0001567	cholesterol 25-hydroxylase activity	Ch25h	IMP		Mouse	MGI:MGI:5440118|PMID:22999953
Molecular Function	GO:0005515	protein binding	CH25H	IPI	UniProtKB:P32242	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CH25H	IPI	UniProtKB:P60329	Human	PMID:32296183
Molecular Function	GO:0008395	steroid hydroxylase activity	Ch25h	IDA		Mouse	PMID:9852097
Biological Process	GO:0035754	B cell chemotaxis	Ch25h	IMP		Mouse	MGI:MGI:5440118|PMID:22999953
Biological Process	GO:0008203	cholesterol metabolic process	CH25H	IDA		Human	PMID:33239446
Biological Process	GO:0008203	cholesterol metabolic process	Ch25h	IDA		Mouse	PMID:9852097
Biological Process	GO:0051607	defense response to virus	ch25h	IDA		Zfish	PMID:28789986
Biological Process	GO:0090206	negative regulation of cholesterol metabolic process	Ch25h	IDA		Mouse	MGI:MGI:6101070|PMID:29033131
Biological Process	GO:1903914	negative regulation of fusion of virus membrane with host plasma membrane	CH25H	IDA		Human	PMID:32944968
Biological Process	GO:1903914	negative regulation of fusion of virus membrane with host plasma membrane	CH25H	IDA		Human	PMID:33239446
Biological Process	GO:0034340	response to type I interferon	CH25H	IDA		Human	PMID:33239446

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern