Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CERK
  • Mouse genes Cerk
  • Rat genes Cerk
  • Zfish genes cerk
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cerk

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001729	ceramide kinase activity	CERK	IDA		Human	PMID:11956206
Molecular Function	GO:0001729	ceramide kinase activity	CERK	IDA		Human	PMID:16269826
Molecular Function	GO:0001729	ceramide kinase activity	CERK	IDA		Human	PMID:19501188
Molecular Function	GO:0001729	ceramide kinase activity	Cerk	IDA		Mouse	MGI:MGI:6316457|PMID:16269826
Molecular Function	GO:0001729	ceramide kinase activity	Cerk	IMP	MGI:MGI:3774547	Mouse	PMID:18555012
Molecular Function	GO:0000287	magnesium ion binding	CERK	IDA		Human	PMID:10947957
Molecular Function	GO:0005515	protein binding	CERK	IPI	UniProtKB:P13196	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CERK	IPI	UniProtKB:Q5JR59	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CERK	IPI	UniProtKB:Q7Z3S9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CERK	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CERK	IPI	UniProtKB:O43482	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CERK	IPI	UniProtKB:O76011	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CERK	IPI	UniProtKB:P05813	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CERK	IPI	UniProtKB:P0CG21	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CERK	IPI	UniProtKB:P0DPK4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CERK	IPI	UniProtKB:Q07627	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CERK	IPI	UniProtKB:Q3LI66	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CERK	IPI	UniProtKB:Q3LI70	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CERK	IPI	UniProtKB:Q8IUB9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CERK	IPI	UniProtKB:Q8IUC1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CERK	IPI	UniProtKB:Q8IWZ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CERK	IPI	UniProtKB:Q9BYQ4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CERK	IPI	UniProtKB:Q9BYR7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CERK	IPI	UniProtKB:Q9BYR8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CERK	IPI	UniProtKB:Q9H8W4	Human	PMID:32296183
Cellular Component	GO:0016020	membrane	CERK	IDA		Human	PMID:11956206
Cellular Component	GO:0005739	mitochondrion	Cerk	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005886	plasma membrane	CERK	IDA		Human	PMID:16269826
Biological Process	GO:0006672	ceramide metabolic process	CERK	IDA		Human	PMID:19501188

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern