Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CELSR2
  • Mouse genes Celsr2
  • Rat genes Celsr2
  • Zfish genes celsr2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Celsr2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Celsr2	IPI	UniProtKB:Q7T0S3	Mouse	MGI:MGI:5512932|PMID:23292348
Cellular Component	GO:0005737	cytoplasm	Celsr2	IDA		Mouse	MGI:MGI:3765257|PMID:16484285
Cellular Component	GO:0005886	plasma membrane	Celsr2	IDA		Mouse	MGI:MGI:3765257|PMID:16484285
Cellular Component	GO:0005886	plasma membrane	celsr2	IDA		Zfish	PMID:17130287
Biological Process	GO:0098609	cell-cell adhesion	celsr2	IDA		Zfish	PMID:17130287
Biological Process	GO:0098609	cell-cell adhesion	celsr2	IMP		Zfish	PMID:19091770
Biological Process	GO:0098609	cell-cell adhesion	celsr2	IMP	ZFIN:ZDB-MRPHLNO-070525-3	Zfish	PMID:17130287
Biological Process	GO:0098609	cell-cell adhesion	celsr2	IGI	ZFIN:ZDB-GENO-090423-8,ZFIN:ZDB-MRPHLNO-070122-3,ZFIN:ZDB-MRPHLNO-070122-4	Zfish	PMID:19091770
Biological Process	GO:0033326	cerebrospinal fluid secretion	Celsr2	IGI	MGI:MGI:1858236	Mouse	PMID:20473291
Biological Process	GO:0060271	cilium assembly	Celsr2	IMP	MGI:MGI:3604518	Mouse	PMID:20473291
Biological Process	GO:0060271	cilium assembly	Celsr2	IGI	MGI:MGI:1858236	Mouse	PMID:20473291
Biological Process	GO:0003341	cilium movement	Celsr2	IMP	MGI:MGI:3604518	Mouse	PMID:20473291
Biological Process	GO:0048813	dendrite morphogenesis	Celsr2	IMP		Rat	PMID:15296717|RGD:8553383
Biological Process	GO:0055113	epiboly involved in gastrulation with mouth forming second	celsr2	IGI	ZFIN:ZDB-GENO-090423-8,ZFIN:ZDB-MRPHLNO-070122-3,ZFIN:ZDB-MRPHLNO-070122-4	Zfish	PMID:19091770
Biological Process	GO:0021754	facial nucleus development	celsr2	IMP	ZFIN:ZDB-GENO-070119-6	Zfish	PMID:17079269
Biological Process	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	Celsr2	IDA		Mouse	MGI:MGI:4419080|PMID:15296717
Biological Process	GO:0097475	motor neuron migration	Celsr2	IMP	MGI:MGI:3604518	Mouse	PMID:20631168
Biological Process	GO:0021999	neural plate anterior/posterior regionalization	Celsr2	IDA		Mouse	MGI:MGI:3765258|PMID:12755329
Biological Process	GO:0008104	protein localization	celsr2	IGI	ZFIN:ZDB-GENE-990415-223	Zfish	PMID:17130287
Biological Process	GO:0022407	regulation of cell-cell adhesion	Celsr2	IMP		Rat	PMID:15955893|RGD:1579822
Biological Process	GO:0006355	regulation of DNA-templated transcription	Celsr2	IDA		Mouse	MGI:MGI:3765258|PMID:12755329
Biological Process	GO:0032880	regulation of protein localization	Celsr2	IGI	MGI:MGI:1858236	Mouse	PMID:20473291
Biological Process	GO:0032880	regulation of protein localization	Celsr2	IMP		Mouse	PMID:20473291
Biological Process	GO:0007283	spermatogenesis	Celsr2	IEP		Rat	PMID:10650949|RGD:68759
Biological Process	GO:0021591	ventricular system development	Celsr2	IMP	MGI:MGI:5429210	Mouse	PMID:21746835
Biological Process	GO:0016055	Wnt signaling pathway	Celsr2	IDA		Mouse	MGI:MGI:3765258|PMID:12755329

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern