Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CDT1
  • Mouse genes Cdt1
  • Rat genes Cdt1
  • Zfish genes cdt1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cdt1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	CDT1	IDA		Human	PMID:11125146
Molecular Function	GO:0003677	DNA binding	Cdt1	IDA		Mouse	MGI:MGI:2388867|PMID:12192004
Molecular Function	GO:0005515	protein binding	CDT1	IPI	UniProtKB:O75496	Human	PMID:11125146
Molecular Function	GO:0005515	protein binding	CDT1	IPI	UniProtKB:Q99741	Human	PMID:14672932
Molecular Function	GO:0005515	protein binding	CDT1	IPI	UniProtKB:O75496	Human	PMID:14993212
Molecular Function	GO:0005515	protein binding	CDT1	IPI	UniProtKB:O75496	Human	PMID:15232106
Molecular Function	GO:0005515	protein binding	CDT1	IPI	UniProtKB:Q99741	Human	PMID:15232106
Molecular Function	GO:0005515	protein binding	CDT1	IPI	UniProtKB:O75496	Human	PMID:16482215
Molecular Function	GO:0005515	protein binding	CDT1	IPI	UniProtKB:P12004	Human	PMID:16482215
Molecular Function	GO:0005515	protein binding	CDT1	IPI	UniProtKB:O75496	Human	PMID:17318181
Molecular Function	GO:0005515	protein binding	CDT1	IPI	UniProtKB:O75496	Human	PMID:19906994
Molecular Function	GO:0005515	protein binding	CDT1	IPI	UniProtKB:Q14566	Human	PMID:20202939
Molecular Function	GO:0005515	protein binding	CDT1	IPI	UniProtKB:Q9UFC0	Human	PMID:20932478
Molecular Function	GO:0005515	protein binding	CDT1	IPI	UniProtKB:O75496	Human	PMID:21543332
Molecular Function	GO:0005515	protein binding	CDT1	IPI	UniProtKB:O75496,UniProtKB:O95251	Human	PMID:21856198
Molecular Function	GO:0005515	protein binding	CDT1	IPI	UniProtKB:P12004,UniProtKB:Q13309	Human	PMID:21856198
Molecular Function	GO:0005515	protein binding	CDT1	IPI	UniProtKB:O14777	Human	PMID:22581055
Molecular Function	GO:0005515	protein binding	CDT1	IPI	UniProtKB:O75496	Human	PMID:22581055
Molecular Function	GO:0005515	protein binding	CDT1	IPI	UniProtKB:Q9BZD4	Human	PMID:22581055
Molecular Function	GO:0005515	protein binding	CDT1	IPI	UniProtKB:Q9BQ67	Human	PMID:25990725
Molecular Function	GO:0005515	protein binding	CDT1	IPI	UniProtKB:O75496	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CDT1	IPI	UniProtKB:Q14566	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CDT1	IPI	UniProtKB:Q9UNN5	Human	PMID:26842564
Molecular Function	GO:0005515	protein binding	CDT1	IPI	UniProtKB:O75496	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	CDT1	IPI	UniProtKB:Q86T82	Human	PMID:27296872
Molecular Function	GO:0005515	protein binding	CDT1	IPI	UniProtKB:O75496	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	Cdt1	IPI	UniProtKB:O88513	Mouse	MGI:MGI:3693385|PMID:15286659
Molecular Function	GO:0005515	protein binding	Cdt1	IPI	UniProtKB:O88513|UniProtKB:P97311	Mouse	MGI:MGI:2388867|PMID:12192004
Molecular Function	GO:0005515	protein binding	Cdt1	IPI	UniProtKB:O88513|UniProtKB:P97311	Mouse	MGI:MGI:6810788|PMID:15811859
Molecular Function	GO:0005515	protein binding	cdt1	IPI	UniProtKB:Q7SXL0	Zfish	PMID:19307597
Cellular Component	GO:0000776	kinetochore	CDT1	IDA		Human	PMID:22581055
Cellular Component	GO:0016604	nuclear body	CDT1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	CDT1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	CDT1	IDA		Human	PMID:11125146
Cellular Component	GO:0005634	nucleus	CDT1	IDA		Human	PMID:24217620
Cellular Component	GO:0005634	nucleus	CDT1	IDA		Human	PMID:26842564
Cellular Component	GO:0005634	nucleus	Cdt1	IDA		Mouse	MGI:MGI:3688384|PMID:14993212
Biological Process	GO:0051315	attachment of mitotic spindle microtubules to kinetochore	CDT1	IMP		Human	PMID:22581055
Biological Process	GO:0051301	cell division	CDT1	IMP		Human	PMID:22581055
Biological Process	GO:0007059	chromosome segregation	CDT1	IMP		Human	PMID:22581055
Biological Process	GO:1902426	deactivation of mitotic spindle assembly checkpoint	CDT1	IMP		Human	PMID:22581055
Biological Process	GO:0000076	DNA replication checkpoint signaling	CDT1	IDA		Human	PMID:14672932
Biological Process	GO:0000076	DNA replication checkpoint signaling	Cdt1	IDA		Mouse	MGI:MGI:2388867|PMID:12192004
Biological Process	GO:0071163	DNA replication preinitiation complex assembly	CDT1	IDA		Human	PMID:11125146
Biological Process	GO:0051383	kinetochore organization	CDT1	IMP		Human	PMID:22581055
Biological Process	GO:0000278	mitotic cell cycle	CDT1	IMP		Human	PMID:22581055
Biological Process	GO:0000278	mitotic cell cycle	cdt1	IMP	ZFIN:ZDB-MRPHLNO-070111-2	Zfish	PMID:23082190
Biological Process	GO:0045786	negative regulation of cell cycle	CDT1	IDA		Human	PMID:19906994
Biological Process	GO:2000104	negative regulation of DNA-templated DNA replication	CDT1	IDA		Human	PMID:19906994
Biological Process	GO:1905341	negative regulation of protein localization to kinetochore	CDT1	IMP		Human	PMID:22581055
Biological Process	GO:0035563	positive regulation of chromatin binding	CDT1	IDA		Human	PMID:11125146
Biological Process	GO:0045740	positive regulation of DNA replication	CDT1	IMP		Human	PMID:26842564
Biological Process	GO:2000105	positive regulation of DNA-templated DNA replication	CDT1	IDA		Human	PMID:11125146
Biological Process	GO:1905342	positive regulation of protein localization to kinetochore	CDT1	IMP		Human	PMID:22581055
Biological Process	GO:0031334	positive regulation of protein-containing complex assembly	CDT1	IMP		Human	PMID:22581055
Biological Process	GO:0033044	regulation of chromosome organization	CDT1	IMP		Human	PMID:22581055
Biological Process	GO:1902595	regulation of DNA replication origin binding	CDT1	IDA		Human	PMID:21856198
Biological Process	GO:0030174	regulation of DNA-templated DNA replication initiation	CDT1	IDA		Human	PMID:11125146
Biological Process	GO:0030174	regulation of DNA-templated DNA replication initiation	Cdt1	IDA		Mouse	MGI:MGI:2388867|PMID:12192004
Biological Process	GO:0033262	regulation of nuclear cell cycle DNA replication	Cdt1	IDA		Mouse	PMID:11850834
Biological Process	GO:0072708	response to sorbitol	CDT1	IDA		Human	PMID:21856198

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern