Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CDK5R2
  • Mouse genes Cdk5r2
  • Rat genes Cdk5r2
  • Zfish genes cdk5r2a,cdk5r2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cdk5r2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	Cdk5r2	IPI	UniProtKB:P60710	Mouse	MGI:MGI:6158991|PMID:10683146
Molecular Function	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	Cdk5r2	IDA		Mouse	MGI:MGI:6158991|PMID:10683146
Molecular Function	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	Cdk5r2	IMP	MGI:MGI:2387662	Mouse	PMID:11517264
Cellular Component	GO:0005737	cytoplasm	Cdk5r2	IDA		Mouse	PMID:15123626
Cellular Component	GO:0005737	cytoplasm	Cdk5r2	IDA		Rat	PMID:10683146|RGD:13601989
Cellular Component	GO:0030426	growth cone	Cdk5r2	IDA		Rat	PMID:10683146|RGD:13601989
Cellular Component	GO:0016020	membrane	Cdk5r2	IDA		Rat	PMID:10683146|RGD:13601989
Cellular Component	GO:0043005	neuron projection	Cdk5r2	IDA		Rat	PMID:10683146|RGD:13601989
Biological Process	GO:0021549	cerebellum development	Cdk5r2	IGI	MGI:MGI:101764	Mouse	PMID:11517264
Biological Process	GO:0060059	embryonic retina morphogenesis in camera-type eye	cdk5r2a	IMP	ZFIN:ZDB-MRPHLNO-090106-4	Zfish	PMID:18753621
Biological Process	GO:0060059	embryonic retina morphogenesis in camera-type eye	cdk5r2a	IGI	ZFIN:ZDB-MRPHLNO-090106-2,ZFIN:ZDB-MRPHLNO-090106-4	Zfish	PMID:18753621
Biological Process	GO:0021766	hippocampus development	Cdk5r2	IGI	MGI:MGI:101764	Mouse	PMID:11517264
Biological Process	GO:0021819	layer formation in cerebral cortex	Cdk5r2	IGI	MGI:MGI:101764	Mouse	PMID:11517264
Biological Process	GO:0001764	neuron migration	Cdk5r2	IGI	MGI:MGI:101764	Mouse	PMID:11517264
Biological Process	GO:0045956	positive regulation of calcium ion-dependent exocytosis	Cdk5r2	IDA		Mouse	PMID:15123626
Biological Process	GO:0045860	positive regulation of protein kinase activity	Cdk5r2	IGI	MGI:MGI:101764	Mouse	PMID:11517264
Biological Process	GO:0010842	retina layer formation	cdk5r2a	IGI	ZFIN:ZDB-MRPHLNO-090106-2,ZFIN:ZDB-MRPHLNO-090106-4	Zfish	PMID:18753621
Biological Process	GO:0010842	retina layer formation	cdk5r2a	IMP	ZFIN:ZDB-MRPHLNO-090106-4	Zfish	PMID:18753621
Biological Process	GO:0021722	superior olivary nucleus maturation	Cdk5r2	IGI	MGI:MGI:101764	Mouse	PMID:11517264

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern