Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CDK11A,CDK11B
  • Mouse genes Cdk11b
  • Rat genes Cdk11b
  • Zfish genes cdk11b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cdk11b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	CDK11B	IDA		Human	PMID:12501247
Molecular Function	GO:0005524	ATP binding	CDK11A	IDA		Human	PMID:12501247
Molecular Function	GO:0005515	protein binding	CDK11B	IPI	UniProtKB:Q13153	Human	PMID:12624090
Molecular Function	GO:0005515	protein binding	CDK11B	IPI	UniProtKB:Q13153	Human	PMID:16413544
Molecular Function	GO:0005515	protein binding	CDK11B	IPI	UniProtKB:O00303	Human	PMID:19245811
Molecular Function	GO:0005515	protein binding	CDK11B	IPI	UniProtKB:Q92614	Human	PMID:25965346
Molecular Function	GO:0004674	protein serine/threonine kinase activity	CDK11B	IDA		Human	PMID:12501247
Molecular Function	GO:0004674	protein serine/threonine kinase activity	CDK11A	IDA		Human	PMID:12501247
Molecular Function	GO:0003723	RNA binding	CDK11B	HDA		Human	PMID:22681889
Cellular Component	GO:0005634	nucleus	CDK11B	IDA		Human	PMID:8195233
Cellular Component	GO:0005634	nucleus	CDK11A	IDA		Human	PMID:8195233
Cellular Component	GO:0005634	nucleus	Cdk11b	IDA		Mouse	PMID:15060143
Biological Process	GO:0001824	blastocyst development	Cdk11b	IMP	MGI:MGI:3043373	Mouse	PMID:15060143
Biological Process	GO:2001234	negative regulation of apoptotic signaling pathway	Cdk11b	IMP	MGI:MGI:3043373	Mouse	PMID:15060143
Biological Process	GO:0006468	protein phosphorylation	CDK11B	IDA		Human	PMID:12501247
Biological Process	GO:0006468	protein phosphorylation	CDK11A	IDA		Human	PMID:12501247
Biological Process	GO:0001558	regulation of cell growth	CDK11B	IEP		Human	PMID:10882096
Biological Process	GO:0001558	regulation of cell growth	CDK11A	IEP		Human	PMID:10882096
Biological Process	GO:0007088	regulation of mitotic nuclear division	Cdk11b	IMP	MGI:MGI:3043373	Mouse	PMID:15060143
Biological Process	GO:0050684	regulation of mRNA processing	CDK11B	IDA		Human	PMID:12501247
Biological Process	GO:0050684	regulation of mRNA processing	CDK11A	IDA		Human	PMID:12501247
Biological Process	GO:0007224	smoothened signaling pathway	cdk11b	IDA		Zfish	PMID:18827223

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern