Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CDK10
  • Mouse genes Cdk10
  • Rat genes Cdk10
  • Zfish genes cdk10
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cdk10

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0097472	cyclin-dependent protein kinase activity	Cdk10	IGI	MGI:MGI:1916359	Mouse	PMID:24218572
Molecular Function	GO:0035173	histone kinase activity	cdk10	IDA		Zfish	PMID:23902762
Molecular Function	GO:0016301	kinase activity	cdk10	IDA		Zfish	PMID:23902762
Molecular Function	GO:0005515	protein binding	CDK10	IPI	UniProtKB:P15036	Human	PMID:18242510
Molecular Function	GO:0005515	protein binding	CDK10	IPI	UniProtKB:Q13526	Human	PMID:22158035
Molecular Function	GO:0005515	protein binding	CDK10	IPI	UniProtKB:P08238	Human	PMID:22939624
Molecular Function	GO:0005515	protein binding	CDK10	IPI	UniProtKB:Q16513	Human	PMID:27104747
Molecular Function	GO:0005515	protein binding	CDK10	IPI	UniProtKB:P08238	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	Cdk10	IPI	PR:Q8QZR8	Mouse	PMID:24218572
Molecular Function	GO:0005515	protein binding	cdk10	IPI	RefSeq:NM_001256295	Zfish	PMID:23902762
Molecular Function	GO:0004674	protein serine/threonine kinase activity	CDK10	IDA		Human	PMID:27104747
Cellular Component	GO:0036064	ciliary basal body	CDK10	IDA		Human	PMID:27104747
Cellular Component	GO:0005634	nucleus	CDK10	IDA		Human	PMID:11006117
Biological Process	GO:0016570	histone modification	cdk10	IDA		Zfish	PMID:23902762|ZFIN:ZDB-PUB-130816-36
Biological Process	GO:1902018	negative regulation of cilium assembly	CDK10	IMP		Human	PMID:27104747
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	cdk10	IMP	ZFIN:ZDB-MRPHLNO-131126-4	Zfish	PMID:23902762
Biological Process	GO:0022008	neurogenesis	cdk10	IMP	ZFIN:ZDB-MRPHLNO-131126-4	Zfish	PMID:23902762
Biological Process	GO:0018107	peptidyl-threonine phosphorylation	CDK10	IDA		Human	PMID:27104747
Biological Process	GO:0043410	positive regulation of MAPK cascade	Cdk10	IGI	MGI:MGI:1916359	Mouse	PMID:24218572
Biological Process	GO:0043687	post-translational protein modification	cdk10	IDA		Zfish	PMID:23902762
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	CDK10	IMP		Human	PMID:27104747

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern