Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CDC42EP2
  • Mouse genes Cdc42ep2
  • Rat genes Cdc42ep2
  • Zfish genes cdc42ep2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cdc42ep2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005096	GTPase activator activity	CDC42EP2	IMP		Human	PMID:10430899
Molecular Function	GO:0001515	opioid peptide activity	Cdc42ep2	IPI	PR:Q8R527	Mouse	PMID:10490598
Molecular Function	GO:0005515	protein binding	CDC42EP2	IPI	UniProtKB:Q16181	Human	PMID:11584266
Molecular Function	GO:0005515	protein binding	CDC42EP2	IPI	UniProtKB:P60953	Human	PMID:20936779
Molecular Function	GO:0005515	protein binding	CDC42EP2	IPI	UniProtKB:P60953	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	CDC42EP2	IPI	UniProtKB:P60953	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CDC42EP2	IPI	UniProtKB:Q9UNA1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CDC42EP2	IPI	UniProtKB:Q9Y5B8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CDC42EP2	IPI	UniProtKB:Q9UNA1-2	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	CDC42EP2	IPI	UniProtKB:Q9NQ75-2	Human	PMID:31413325
Molecular Function	GO:0005515	protein binding	CDC42EP2	IPI	UniProtKB:P10606	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDC42EP2	IPI	UniProtKB:P60953	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDC42EP2	IPI	UniProtKB:Q14511-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDC42EP2	IPI	UniProtKB:Q9NQ75-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDC42EP2	IPI	UniProtKB:Q9NRD5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDC42EP2	IPI	UniProtKB:Q9Y5B8	Human	PMID:32296183
Molecular Function	GO:0031267	small GTPase binding	CDC42EP2	IPI	UniProtKB:P60953	Human	PMID:11035016
Cellular Component	GO:0005737	cytoplasm	CDC42EP2	IDA		Human	PMID:11035016
Cellular Component	GO:0005829	cytosol	CDC42EP2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	CDC42EP2	IDA		Human	PMID:11035016
Cellular Component	GO:0015630	microtubule cytoskeleton	CDC42EP2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0045335	phagocytic vesicle	Cdc42ep2	IDA		Mouse	PMID:19144319
Cellular Component	GO:0005886	plasma membrane	CDC42EP2	IDA		Human	PMID:10430899
Biological Process	GO:0030036	actin cytoskeleton organization	CDC42EP2	IDA		Human	PMID:10430899
Biological Process	GO:0071346	cellular response to type II interferon	Cdc42ep2	IDA		Mouse	PMID:19144319
Biological Process	GO:0030838	positive regulation of actin filament polymerization	CDC42EP2	IDA		Human	PMID:11035016
Biological Process	GO:0031274	positive regulation of pseudopodium assembly	CDC42EP2	IDA		Human	PMID:11035016
Biological Process	GO:0008360	regulation of cell shape	CDC42EP2	IDA		Human	PMID:11035016

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern