Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CD276
  • Mouse genes Cd276
  • Rat genes Cd276
  • Zfish genes cd276
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cd276

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	Cd276	IPI	UniProtKB:Q8VE98	Mouse	MGI:MGI:5914141|PMID:23583036
Molecular Function	GO:0005515	protein binding	CD276	IPI	UniProtKB:Q5T2D2	Human	PMID:18650384
Molecular Function	GO:0005102	signaling receptor binding	Cd276	IDA		Mouse	PMID:12055244
Molecular Function	GO:0005102	signaling receptor binding	Cd276	IMP	MGI:MGI:3033707	Mouse	PMID:12925852
Molecular Function	GO:0005102	signaling receptor binding	Cd276	IDA		Mouse	PMID:16751379
Cellular Component	GO:0009897	external side of plasma membrane	Cd276	IDA		Mouse	PMID:12925852
Cellular Component	GO:0009897	external side of plasma membrane	Cd276	IDA		Mouse	PMID:15317945
Biological Process	GO:0050728	negative regulation of inflammatory response	Cd276	IMP	MGI:MGI:3033707	Mouse	PMID:12925852
Biological Process	GO:0032703	negative regulation of interleukin-2 production	Cd276	IDA		Mouse	PMID:12925852
Biological Process	GO:0042130	negative regulation of T cell proliferation	Cd276	IDA		Mouse	PMID:12925852
Biological Process	GO:0042130	negative regulation of T cell proliferation	Cd276	IMP	MGI:MGI:3033707	Mouse	PMID:12925852
Biological Process	GO:0032689	negative regulation of type II interferon production	Cd276	IMP	MGI:MGI:3033707	Mouse	PMID:12925852
Biological Process	GO:0032689	negative regulation of type II interferon production	Cd276	IDA		Mouse	PMID:12925852
Biological Process	GO:0030501	positive regulation of bone mineralization	Cd276	IMP	MGI:MGI:3033707	Mouse	PMID:15317945
Biological Process	GO:0032743	positive regulation of interleukin-2 production	Cd276	IMP		Mouse	PMID:16751379
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	Cd276	IMP	MGI:MGI:3033707	Mouse	PMID:15317945
Biological Process	GO:0042102	positive regulation of T cell proliferation	CD276	IDA		Human	PMID:11224528
Biological Process	GO:0042102	positive regulation of T cell proliferation	Cd276	IMP		Mouse	PMID:16751379
Biological Process	GO:0032729	positive regulation of type II interferon production	CD276	IDA		Human	PMID:11224528
Biological Process	GO:0050776	regulation of immune response	Cd276	IMP	MGI:MGI:3033707	Mouse	PMID:12925852
Biological Process	GO:0042110	T cell activation	CD276	IDA		Human	PMID:18650384
Biological Process	GO:0042098	T cell proliferation	Cd276	IMP	MGI:MGI:3033707	Mouse	PMID:12925852
Biological Process	GO:0042098	T cell proliferation	Cd276	IDA		Mouse	PMID:12925852

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern