Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CD244
  • Mouse genes Cd244a
  • Rat genes Cd244
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cd244a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042288	MHC class I protein binding	CD244	IDA		Human	PMID:20164429
Molecular Function	GO:0005515	protein binding	CD244	IPI	UniProtKB:O60880	Human	PMID:11489943
Molecular Function	GO:0005515	protein binding	CD244	IPI	UniProtKB:P29350	Human	PMID:11489943
Molecular Function	GO:0005515	protein binding	CD244	IPI	UniProtKB:P09326	Human	PMID:15153464
Molecular Function	GO:0005515	protein binding	CD244	IPI	UniProtKB:O60880-1	Human	PMID:15841490
Molecular Function	GO:0005515	protein binding	CD244	IPI	UniProtKB:P09326	Human	PMID:16002700
Molecular Function	GO:0005515	protein binding	CD244	IPI	UniProtKB:O60880	Human	PMID:16920955
Molecular Function	GO:0005515	protein binding	CD244	IPI	UniProtKB:O60880-1	Human	PMID:16983070
Molecular Function	GO:0005515	protein binding	CD244	IPI	UniProtKB:P09326	Human	PMID:18296487
Molecular Function	GO:0005515	protein binding	CD244	IPI	UniProtKB:P61769	Human	PMID:20164429
Molecular Function	GO:0005515	protein binding	CD244	IPI	UniProtKB:O14796	Human	PMID:23346089
Molecular Function	GO:0005515	protein binding	CD244	IPI	UniProtKB:O60880	Human	PMID:23346089
Molecular Function	GO:0005515	protein binding	CD244	IPI	UniProtKB:O14796	Human	PMID:24642916
Molecular Function	GO:0005515	protein binding	CD244	IPI	UniProtKB:O60880	Human	PMID:24642916
Molecular Function	GO:0005515	protein binding	CD244	IPI	UniProtKB:P19174	Human	PMID:24642916
Molecular Function	GO:0005515	protein binding	CD244	IPI	UniProtKB:P29350	Human	PMID:24642916
Molecular Function	GO:0005515	protein binding	CD244	IPI	UniProtKB:Q06124	Human	PMID:24642916
Molecular Function	GO:0005515	protein binding	CD244	IPI	UniProtKB:Q92835	Human	PMID:24642916
Molecular Function	GO:0005515	protein binding	CD244	IPI	UniProtKB:O60880	Human	PMID:26221972
Molecular Function	GO:0005515	protein binding	CD244	IPI	UniProtKB:Q92835	Human	PMID:26221972
Molecular Function	GO:0005515	protein binding	Cd244a	IPI	PR:O35324	Mouse	PMID:16127454
Molecular Function	GO:0005515	protein binding	Cd244a	IPI	PR:Q45HK4	Mouse	PMID:16127454
Cellular Component	GO:0009897	external side of plasma membrane	CD244	IDA		Human	PMID:17213291
Cellular Component	GO:0009897	external side of plasma membrane	Cd244a	IDA		Mouse	PMID:10072077
Biological Process	GO:0001773	myeloid dendritic cell activation	Cd244a	IMP		Mouse	MGI:MGI:5700282|PMID:25643613
Biological Process	GO:0002323	natural killer cell activation involved in immune response	CD244	IDA		Human	PMID:11714776
Biological Process	GO:0002323	natural killer cell activation involved in immune response	Cd244a	IMP		Mouse	MGI:MGI:3773416|PMID:15905190
Biological Process	GO:2000566	positive regulation of CD8-positive, alpha-beta T cell proliferation	Cd244a	IMP		Mouse	MGI:MGI:5700312|PMID:11739483
Biological Process	GO:0071663	positive regulation of granzyme B production	CD244	IDA		Human	PMID:11714776
Biological Process	GO:0060732	positive regulation of inositol phosphate biosynthetic process	CD244	IDA		Human	PMID:8376943
Biological Process	GO:0032757	positive regulation of interleukin-8 production	CD244	IDA		Human	PMID:8376943
Biological Process	GO:0032819	positive regulation of natural killer cell proliferation	Cd244a	IMP		Mouse	MGI:MGI:3773416|PMID:15905190
Biological Process	GO:0032729	positive regulation of type II interferon production	CD244	IDA		Human	PMID:11714776

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern