Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CCKAR
  • Mouse genes Cckar
  • Rat genes Cckar
  • Zfish genes cckar
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cckar

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004951	cholecystokinin receptor activity	CCKAR	IDA		Human	PMID:8503909
Molecular Function	GO:0004951	cholecystokinin receptor activity	Cckar	IDA		Rat	PMID:18776046|RGD:2313306
Molecular Function	GO:0017046	peptide hormone binding	CCKAR	IPI	CHEBI:80327	Human	PMID:8503909
Cellular Component	GO:0005737	cytoplasm	Cckar	IDA		Rat	PMID:10535877|RGD:2313330
Cellular Component	GO:0005829	cytosol	CCKAR	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005783	endoplasmic reticulum	Cckar	IDA		Rat	PMID:9169450|RGD:2313345
Cellular Component	GO:0005768	endosome	Cckar	IDA		Rat	PMID:9169450|RGD:2313345
Cellular Component	GO:0005764	lysosome	Cckar	IDA		Rat	PMID:9169450|RGD:2313345
Cellular Component	GO:0016020	membrane	CCKAR	IDA		Human	PMID:8503909
Cellular Component	GO:0005654	nucleoplasm	CCKAR	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	CCKAR	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Cckar	IDA		Rat	PMID:10535877|RGD:2313330
Cellular Component	GO:0043195	terminal bouton	Cckar	IDA		Rat	PMID:3408996|RGD:2313271
Biological Process	GO:0031532	actin cytoskeleton reorganization	Cckar	IDA		Rat	PMID:11891013|RGD:2313349
Biological Process	GO:0031100	animal organ regeneration	Cckar	IEP		Rat	PMID:10403848|RGD:2313336
Biological Process	GO:0007409	axonogenesis	Cckar	IMP		Mouse	PMID:15152034
Biological Process	GO:0032870	cellular response to hormone stimulus	Cckar	IEP		Rat	PMID:12649564|RGD:2313308
Biological Process	GO:0038188	cholecystokinin signaling pathway	CCKAR	IDA		Human	PMID:8503909
Biological Process	GO:0042755	eating behavior	Cckar	IMP		Rat	PMID:16728725|RGD:2313288
Biological Process	GO:0007631	feeding behavior	Cckar	IDA		Rat	PMID:12414437|RGD:634706
Biological Process	GO:0030900	forebrain development	Cckar	IMP	MGI:MGI:3051882	Mouse	PMID:15152034
Biological Process	GO:0001696	gastric acid secretion	Cckar	IDA		Rat	PMID:9773935|RGD:2313338
Biological Process	GO:0030073	insulin secretion	Cckar	IDA		Rat	PMID:9773935|RGD:2313338
Biological Process	GO:0001764	neuron migration	Cckar	IMP		Mouse	PMID:15152034
Biological Process	GO:0031016	pancreas development	Cckar	IEP		Rat	PMID:10403848|RGD:2313336
Biological Process	GO:0030157	pancreatic juice secretion	Cckar	IMP		Rat	PMID:16327284|RGD:2313374
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	Cckar	IDA		Rat	PMID:18776046|RGD:2313306
Biological Process	GO:0090274	positive regulation of somatostatin secretion	Cckar	IMP		Rat	PMID:19959964|RGD:4110825
Biological Process	GO:0002023	reduction of food intake in response to dietary excess	Cckar	IMP		Rat	PMID:12840200|RGD:2313380
Biological Process	GO:0051924	regulation of calcium ion transport	Cckar	IDA		Rat	PMID:11207382|RGD:2313351
Biological Process	GO:0046883	regulation of hormone secretion	Cckar	IDA		Rat	PMID:15979947|RGD:2313293
Biological Process	GO:0043266	regulation of potassium ion transport	Cckar	IDA		Rat	PMID:12427859|RGD:2313323
Biological Process	GO:0051384	response to glucocorticoid	Cckar	IEP		Rat	PMID:7977738|RGD:2313346
Biological Process	GO:0009408	response to heat	Cckar	IMP		Rat	PMID:16891771|RGD:2313358
Biological Process	GO:0032496	response to lipopolysaccharide	Cckar	IEP		Rat	PMID:17622698|RGD:2313275
Biological Process	GO:0007584	response to nutrient	Cckar	IEP		Rat	PMID:15127944|RGD:2313376
Biological Process	GO:0009314	response to radiation	Cckar	IEP		Rat	PMID:16472889|RGD:2313291
Biological Process	GO:0042594	response to starvation	Cckar	IMP		Rat	PMID:12954406|RGD:2313307
Biological Process	GO:0048545	response to steroid hormone	Cckar	IEP		Rat	PMID:16786113|RGD:2313277
Biological Process	GO:0001659	temperature homeostasis	Cckar	IMP		Rat	PMID:15178543|RGD:1625204

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern