Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CBR3
  • Mouse genes Cbr3
  • Rat genes Cbr3
  • Zfish genes cbr1,cbr1l
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cbr3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0000253	3-keto sterol reductase activity	Cbr3	IDA		Rat	PMID:18983987|RGD:2316293
Molecular Function	GO:0004090	carbonyl reductase (NADPH) activity	CBR3	IDA		Human	PMID:18493841
Molecular Function	GO:0004090	carbonyl reductase (NADPH) activity	Cbr3	IDA		Rat	PMID:18983987|RGD:2316293
Molecular Function	GO:0070402	NADPH binding	CBR3	IDA		Human	PMID:18493841
Molecular Function	GO:0008753	NADPH dehydrogenase (quinone) activity	CBR3	IDA		Human	PMID:19841672
Molecular Function	GO:0005515	protein binding	CBR3	IPI	UniProtKB:O00560	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	CBR3	IPI	UniProtKB:O00560	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CBR3	IPI	UniProtKB:O00560	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBR3	IPI	UniProtKB:Q8TD16-2	Human	PMID:32296183
Cellular Component	GO:0005829	cytosol	CBR3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	CBR3	IDA		Human	PMID:18493841
Cellular Component	GO:0005615	extracellular space	CBR3	HDA		Human	PMID:22664934
Cellular Component	GO:0005654	nucleoplasm	CBR3	IDA		Human	GO_REF:0000052
Biological Process	GO:0050890	cognition	CBR3	IMP		Human	PMID:23227193
Biological Process	GO:0042376	phylloquinone catabolic process	Cbr3	IDA		Rat	PMID:18983987|RGD:2316293

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern