Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CASTOR1
  • Mouse genes Castor1
  • Rat genes Castor1
  • Zfish genes castor1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Castor1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0034618	arginine binding	CASTOR1	IDA		Human	PMID:26972053
Molecular Function	GO:0034618	arginine binding	CASTOR1	IDA		Human	PMID:33594058
Molecular Function	GO:0042802	identical protein binding	CASTOR1	IPI	UniProtKB:Q8WTX7	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	CASTOR1	IDA		Human	PMID:26972053
Molecular Function	GO:0042802	identical protein binding	CASTOR1	IPI	UniProtKB:Q8WTX7	Human	PMID:32296183
Molecular Function	GO:0140678	molecular function inhibitor activity	CASTOR1	IDA		Human	PMID:26972053
Molecular Function	GO:0005515	protein binding	CASTOR1	IPI	UniProtKB:Q96GY0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CASTOR1	IPI	UniProtKB:Q96EE3	Human	PMID:26972053
Molecular Function	GO:0005515	protein binding	CASTOR1	IPI	UniProtKB:Q96S15	Human	PMID:26972053
Molecular Function	GO:0005515	protein binding	CASTOR1	IPI	UniProtKB:Q9NXC5	Human	PMID:26972053
Molecular Function	GO:0005515	protein binding	CASTOR1	IPI	UniProtKB:Q96GY0	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CASTOR1	IPI	UniProtKB:O14894	Human	PMID:30956113
Molecular Function	GO:0005515	protein binding	CASTOR1	IPI	UniProtKB:Q16401	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CASTOR1	IPI	UniProtKB:Q5TFG8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CASTOR1	IPI	UniProtKB:Q96EY4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CASTOR1	IPI	UniProtKB:Q96GY0	Human	PMID:32296183
Molecular Function	GO:0140311	protein sequestering activity	CASTOR1	IDA		Human	PMID:33594058
Molecular Function	GO:0140299	small molecule sensor activity	CASTOR1	IDA		Human	PMID:26972053
Cellular Component	GO:0005829	cytosol	CASTOR1	IDA		Human	PMID:26972053
Biological Process	GO:1903577	cellular response to L-arginine	CASTOR1	IDA		Human	PMID:26972053
Biological Process	GO:1903577	cellular response to L-arginine	CASTOR1	IMP		Human	PMID:26972053
Biological Process	GO:1903577	cellular response to L-arginine	CASTOR1	IDA		Human	PMID:33594058
Biological Process	GO:1904262	negative regulation of TORC1 signaling	CASTOR1	IDA		Human	PMID:26972053
Biological Process	GO:1904262	negative regulation of TORC1 signaling	CASTOR1	IMP		Human	PMID:26972053
Biological Process	GO:1904262	negative regulation of TORC1 signaling	CASTOR1	IDA		Human	PMID:33594058
Biological Process	GO:1904263	positive regulation of TORC1 signaling	CASTOR1	IDA		Human	PMID:26972053

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern