Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CA3
  • Mouse genes Car3
  • Rat genes Car3
  • Zfish genes cahz
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Car3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004089	carbonate dehydratase activity	CA3	IDA		Human	PMID:18618712
Molecular Function	GO:0004089	carbonate dehydratase activity	cahz	IGI	ZFIN:ZDB-MRPHLNO-100517-5,ZFIN:ZDB-MRPHLNO-100517-6	Zfish	PMID:19915126
Molecular Function	GO:0004089	carbonate dehydratase activity	cahz	IMP	ZFIN:ZDB-MRPHLNO-100517-5	Zfish	PMID:19915126
Molecular Function	GO:0016151	nickel cation binding	Car3	IDA		Mouse	PMID:9020864
Molecular Function	GO:0016791	phosphatase activity	Car3	IDA		Rat	PMID:8633035|RGD:10047300
Molecular Function	GO:0005515	protein binding	CA3	IPI	UniProtKB:P37235	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CA3	IPI	UniProtKB:Q9BS40	Human	PMID:32296183
Cellular Component	GO:0005737	cytoplasm	Car3	IDA		Rat	PMID:15928319|RGD:155226874
Cellular Component	GO:0005829	cytosol	CA3	IDA		Human	PMID:18618712
Cellular Component	GO:0005829	cytosol	Car3	IDA		Mouse	PMID:24789143
Cellular Component	GO:0005829	cytosol	Car3	IDA		Rat	PMID:19239903|RGD:7242903
Biological Process	GO:0015670	carbon dioxide transport	cahz	IMP	ZFIN:ZDB-MRPHLNO-100517-5	Zfish	PMID:19915126
Biological Process	GO:0015670	carbon dioxide transport	cahz	IGI	ZFIN:ZDB-MRPHLNO-100517-5,ZFIN:ZDB-MRPHLNO-100517-6	Zfish	PMID:19915126
Biological Process	GO:0042539	hypotonic salinity response	cahz	IDA		Zfish	PMID:17299134
Biological Process	GO:0009617	response to bacterium	Car3	IEP		Mouse	PMID:23012479
Biological Process	GO:0045471	response to ethanol	Car3	IEP		Rat	PMID:19239903|RGD:7242903
Biological Process	GO:0006979	response to oxidative stress	Car3	IMP		Rat	PMID:10900145|RGD:634677

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern