Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CAPZA1
  • Mouse genes Capza1
  • Rat genes Capza1
  • Zfish genes capza1a,capza1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Capza1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051015	actin filament binding	Capza1	IDA		Mouse	PMID:17656356
Molecular Function	GO:0045296	cadherin binding	CAPZA1	HDA		Human	PMID:25468996
Molecular Function	GO:0005515	protein binding	CAPZA1	IPI	UniProtKB:Q9Y3L3	Human	PMID:22891260
Molecular Function	GO:0005515	protein binding	CAPZA1	IPI	UniProtKB:Q9Y5K6	Human	PMID:22891260
Molecular Function	GO:0005515	protein binding	CAPZA1	IPI	UniProtKB:Q96B97	Human	PMID:23178720
Molecular Function	GO:0005515	protein binding	CAPZA1	IPI	UniProtKB:Q96B97	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CAPZA1	IPI	UniProtKB:Q6ZU35	Human	PMID:30361697
Molecular Function	GO:0005515	protein binding	CAPZA1	IPI	UniProtKB:P04271	Human	PMID:31837246
Molecular Function	GO:0005515	protein binding	CAPZA1	IPI	UniProtKB:P23297	Human	PMID:31837246
Molecular Function	GO:0005515	protein binding	CAPZA1	IPI	UniProtKB:P25815	Human	PMID:31837246
Molecular Function	GO:0005515	protein binding	CAPZA1	IPI	UniProtKB:P33763	Human	PMID:31837246
Molecular Function	GO:0005515	protein binding	CAPZA1	IPI	UniProtKB:Q96B97	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	Capza1	IPI	PR:Q91YR1	Mouse	PMID:11604420
Molecular Function	GO:0005515	protein binding	Capza1	IPI	PR:Q3V3V9	Mouse	PMID:23793062
Cellular Component	GO:0005903	brush border	Capza1	IDA		Mouse	MGI:MGI:5621262|PMID:22114352
Cellular Component	GO:0005911	cell-cell junction	Capza1	IDA		Mouse	PMID:23793062
Cellular Component	GO:0030863	cortical cytoskeleton	Capza1	IDA		Mouse	PMID:18723693
Cellular Component	GO:0070062	extracellular exosome	CAPZA1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	CAPZA1	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	CAPZA1	HDA		Human	PMID:23533145
Cellular Component	GO:0008290	F-actin capping protein complex	Capza1	IDA		Mouse	PMID:11604420
Cellular Component	GO:0016020	membrane	Capza1	IDA		Mouse	PMID:18723693
Cellular Component	GO:0071203	WASH complex	CAPZA1	IDA		Human	PMID:19922875
Cellular Component	GO:0030018	Z disc	capza1a	IDA		Zfish	PMID:18347070
Biological Process	GO:0051016	barbed-end actin filament capping	Capza1	IDA		Mouse	PMID:17656356
Biological Process	GO:0034329	cell junction assembly	CAPZA1	IMP		Human	PMID:22891260

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern