Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Cacnb4

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes CACNB4
- Mouse genes Cacnb4
- Rat genes Cacnb4
- Zfish genes cacnb4a,cacnb4b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cacnb4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008331	high voltage-gated calcium channel activity	CACNB4	IDA		Human	PMID:11880487
Molecular Function	GO:0005515	protein binding	CACNB4	IPI	UniProtKB:Q5JST6	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	CACNB4	IPI	UniProtKB:P56545-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CACNB4	IPI	UniProtKB:Q5JST6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CACNB4	IPI	UniProtKB:Q68D86	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Cacnb4	IPI	UniProtKB:Q66L44	Mouse	MGI:MGI:5607190\|PMID:24751537
Molecular Function	GO:0005515	protein binding	Cacnb4	IPI	UniProtKB:Q8IUD2-2	Mouse	MGI:MGI:5508718\|PMID:22107844
Molecular Function	GO:0005515	protein binding	Cacnb4	IPI	UniProtKB:Q91V89	Mouse	MGI:MGI:5441119\|PMID:22892567
Molecular Function	GO:0005515	protein binding	Cacnb4	IPI	PR:O55017	Mouse	PMID:10328888
Molecular Function	GO:0005515	protein binding	Cacnb4	IPI	PR:P97445	Mouse	PMID:10328888
Molecular Function	GO:0005515	protein binding	Cacnb4	IPI	UniProtKB:P27884	Rat	PMID:11988102\|RGD:634754
Molecular Function	GO:0005515	protein binding	Cacnb4	IPI	UniProtKB:P63058	Rat	PMID:22892567\|RGD:11059566
Molecular Function	GO:0005515	protein binding	Cacnb4	IPI	UniProtKB:Q91V89	Rat	PMID:22892567\|RGD:11059566
Molecular Function	GO:0019901	protein kinase binding	Cacnb4	IDA		Rat	PMID:18205403\|RGD:7175532
Molecular Function	GO:0005245	voltage-gated calcium channel activity	CACNB4	IDA		Human	PMID:16525042
Molecular Function	GO:0005245	voltage-gated calcium channel activity	Cacnb4	IMP	MGI:MGI:1856936	Mouse	PMID:12151514
Molecular Function	GO:0005245	voltage-gated calcium channel activity	Cacnb4	IMP	MGI:MGI:1856936	Mouse	PMID:9705268
Molecular Function	GO:0005245	voltage-gated calcium channel activity	Cacnb4	IMP		Rat	PMID:12821675\|RGD:737839
Molecular Function	GO:0005245	voltage-gated calcium channel activity	cacnb4b	IDA		Zfish	PMID:25650925
Molecular Function	GO:0099626	voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels	Cacnb4	IMP		Mouse	PMID:10322048
Molecular Function	GO:0099626	voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels	Cacnb4	IDA		Mouse	PMID:10322048
Cellular Component	GO:0005737	cytoplasm	Cacnb4	IDA		Rat	PMID:28587927\|RGD:13515054
Cellular Component	GO:0098978	glutamatergic synapse	Cacnb4	IMP		Mouse	PMID:10322048
Cellular Component	GO:0098978	glutamatergic synapse	Cacnb4	IDA		Mouse	PMID:10322048
Cellular Component	GO:0016607	nuclear speck	Cacnb4	IDA		Rat	PMID:28587927\|RGD:13515054
Cellular Component	GO:0005730	nucleolus	Cacnb4	IDA		Rat	PMID:28587927\|RGD:13515054
Cellular Component	GO:0098793	presynapse	Cacnb4	IDA		Rat	PMID:10931840\|RGD:13702389
Cellular Component	GO:0098793	presynapse	Cacnb4	IMP		Rat	PMID:10931840\|RGD:13702389
Cellular Component	GO:0005891	voltage-gated calcium channel complex	CACNB4	IDA		Human	PMID:11880487
Cellular Component	GO:0005891	voltage-gated calcium channel complex	CACNB4	IDA		Human	PMID:16525042
Cellular Component	GO:0005891	voltage-gated calcium channel complex	Cacnb4	IMP	MGI:MGI:1856936	Mouse	PMID:9705268
Cellular Component	GO:0005891	voltage-gated calcium channel complex	Cacnb4	IDA		Mouse	PMID:10328888
Biological Process	GO:0007628	adult walking behavior	Cacnb4	IMP	MGI:MGI:1856936	Mouse	PMID:10328888
Biological Process	GO:0007628	adult walking behavior	Cacnb4	IMP	MGI:MGI:1856936	Mouse	PMID:12223573
Biological Process	GO:0007628	adult walking behavior	Cacnb4	IMP	MGI:MGI:1856936	Mouse	PMID:7562514
Biological Process	GO:0006816	calcium ion transport	Cacnb4	IMP	MGI:MGI:1856936	Mouse	PMID:10407181
Biological Process	GO:0006816	calcium ion transport	Cacnb4	IMP	MGI:MGI:1856936	Mouse	PMID:7595494
Biological Process	GO:0006816	calcium ion transport	Cacnb4	IMP		Rat	PMID:12821675\|RGD:737839
Biological Process	GO:0046058	cAMP metabolic process	Cacnb4	IMP	MGI:MGI:1856936	Mouse	PMID:7595494
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	Cacnb4	IEP		Mouse	PMID:20439489
Biological Process	GO:0050908	detection of light stimulus involved in visual perception	Cacnb4	IMP	MGI:MGI:1856936	Mouse	PMID:16636205
Biological Process	GO:0055113	epiboly involved in gastrulation with mouth forming second	cacnb4b	IMP	ZFIN:ZDB-MRPHLNO-090114-4	Zfish	PMID:18172207
Biological Process	GO:0055113	epiboly involved in gastrulation with mouth forming second	cacnb4a	IMP	ZFIN:ZDB-MRPHLNO-090114-3	Zfish	PMID:18172207
Biological Process	GO:0014051	gamma-aminobutyric acid secretion	Cacnb4	IMP	MGI:MGI:1856936	Mouse	PMID:7595494
Biological Process	GO:0007214	gamma-aminobutyric acid signaling pathway	Cacnb4	IMP	MGI:MGI:1856936	Mouse	PMID:7472490
Biological Process	GO:0007214	gamma-aminobutyric acid signaling pathway	Cacnb4	IMP	MGI:MGI:1856936	Mouse	PMID:8388308
Biological Process	GO:0007214	gamma-aminobutyric acid signaling pathway	Cacnb4	IMP	MGI:MGI:1856936	Mouse	PMID:7562514
Biological Process	GO:0006874	intracellular calcium ion homeostasis	Cacnb4	IMP	MGI:MGI:1856936	Mouse	PMID:15637280
Biological Process	GO:0055001	muscle cell development	Cacnb4	IMP	MGI:MGI:1856936	Mouse	PMID:17320843
Biological Process	GO:0008285	negative regulation of cell population proliferation	Cacnb4	IDA		Rat	PMID:28587927\|RGD:13515054
Biological Process	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	Cacnb4	IDA		Rat	PMID:28587927\|RGD:13515054
Biological Process	GO:0050877	nervous system process	Cacnb4	IMP	MGI:MGI:1856936	Mouse	PMID:1321503
Biological Process	GO:0050877	nervous system process	Cacnb4	IMP	MGI:MGI:1856936	Mouse	PMID:9293489
Biological Process	GO:0007528	neuromuscular junction development	Cacnb4	IMP	MGI:MGI:1856936	Mouse	PMID:17320843
Biological Process	GO:0019227	neuronal action potential propagation	Cacnb4	IMP	MGI:MGI:1856936	Mouse	PMID:7261997
Biological Process	GO:0048541	Peyer's patch development	Cacnb4	IMP	MGI:MGI:1856936	Mouse	PMID:5037658
Biological Process	GO:1904751	positive regulation of protein localization to nucleolus	Cacnb4	IDA		Rat	PMID:28587927\|RGD:13515054
Biological Process	GO:1901387	positive regulation of voltage-gated calcium channel activity	Cacnb4	IDA		Rat	PMID:12821675\|RGD:737839
Biological Process	GO:0042391	regulation of membrane potential	Cacnb4	IMP	MGI:MGI:1856936	Mouse	PMID:15637280
Biological Process	GO:0042391	regulation of membrane potential	Cacnb4	IMP	MGI:MGI:1856936	Mouse	PMID:12151514
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	Cacnb4	IDA		Mouse	PMID:10322048
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	Cacnb4	IMP		Mouse	PMID:10322048
Biological Process	GO:1901385	regulation of voltage-gated calcium channel activity	CACNB4	IMP		Human	PMID:11880487
Biological Process	GO:0048536	spleen development	Cacnb4	IMP	MGI:MGI:1856936	Mouse	PMID:5037658
Biological Process	GO:0035249	synaptic transmission, glutamatergic	Cacnb4	IMP	MGI:MGI:1856936	Mouse	PMID:10322048
Biological Process	GO:0050852	T cell receptor signaling pathway	Cacnb4	IMP	MGI:MGI:1856936	Mouse	PMID:15637280
Biological Process	GO:0050852	T cell receptor signaling pathway	Cacnb4	IMP	MGI:MGI:1856936	Mouse	PMID:17028169
Biological Process	GO:0048538	thymus development	Cacnb4	IMP	MGI:MGI:1856936	Mouse	PMID:5037658

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.