Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CACNA1E
  • Mouse genes Cacna1e
  • Rat genes Cacna1e
  • Zfish genes cacna1eb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cacna1e

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Cacna1e	IPI	UniProtKB:Q9D9T8	Mouse	MGI:MGI:3688350|PMID:15258581
Molecular Function	GO:0005245	voltage-gated calcium channel activity	CACNA1E	IDA		Human	PMID:8071363
Molecular Function	GO:0005245	voltage-gated calcium channel activity	Cacna1e	IMP	MGI:MGI:2179732	Mouse	PMID:11959138
Molecular Function	GO:0005245	voltage-gated calcium channel activity	Cacna1e	IMP		Mouse	PMID:12827191
Molecular Function	GO:0005245	voltage-gated calcium channel activity	Cacna1e	IMP	MGI:MGI:2180170	Mouse	PMID:11102459
Molecular Function	GO:0005245	voltage-gated calcium channel activity	Cacna1e	IMP	MGI:MGI:3526823	Mouse	PMID:15630454
Molecular Function	GO:0005245	voltage-gated calcium channel activity	Cacna1e	IMP	MGI:MGI:3526823	Mouse	PMID:14976402
Molecular Function	GO:0005245	voltage-gated calcium channel activity	Cacna1e	IMP	MGI:MGI:2451031	Mouse	PMID:11854466
Molecular Function	GO:0005245	voltage-gated calcium channel activity	Cacna1e	IMP		Mouse	PMID:12074836
Molecular Function	GO:0005245	voltage-gated calcium channel activity	Cacna1e	IMP	MGI:MGI:3526823	Mouse	PMID:17369816
Molecular Function	GO:0005245	voltage-gated calcium channel activity	Cacna1e	IDA		Rat	PMID:21611731|RGD:7205480
Molecular Function	GO:0099626	voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels	Cacna1e	EXP		Rat	PMID:19193890|RGD:13792544
Molecular Function	GO:0099626	voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels	Cacna1e	IDA		Rat	PMID:19193890|RGD:13792544
Molecular Function	GO:0022843	voltage-gated monoatomic cation channel activity	CACNA1E	IDA		Human	PMID:30343943
Cellular Component	GO:0098982	GABA-ergic synapse	Cacna1e	EXP		Rat	PMID:19193890|RGD:13792544
Cellular Component	GO:0098982	GABA-ergic synapse	Cacna1e	IDA		Rat	PMID:19193890|RGD:13792544
Cellular Component	GO:0043204	perikaryon	Cacna1e	IDA		Rat	PMID:16736476|RGD:1582593
Cellular Component	GO:0045211	postsynaptic membrane	Cacna1e	IDA		Mouse	PMID:23015445
Cellular Component	GO:0042734	presynaptic membrane	Cacna1e	IDA		Mouse	PMID:23015445
Cellular Component	GO:0005891	voltage-gated calcium channel complex	Cacna1e	IMP	MGI:MGI:2388392	Mouse	PMID:16924481
Cellular Component	GO:0005891	voltage-gated calcium channel complex	Cacna1e	IDA		Rat	PMID:21611731|RGD:7205480
Biological Process	GO:0001662	behavioral fear response	Cacna1e	IMP	MGI:MGI:2451031	Mouse	PMID:11854466
Biological Process	GO:0048266	behavioral response to pain	Cacna1e	IMP	MGI:MGI:2179732	Mouse	PMID:10801976
Biological Process	GO:0070509	calcium ion import	Cacna1e	IDA		Rat	PMID:21611731|RGD:7205480
Biological Process	GO:0070588	calcium ion transmembrane transport	Cacna1e	IMP		Mouse	PMID:12074836
Biological Process	GO:0070588	calcium ion transmembrane transport	Cacna1e	IMP	MGI:MGI:3526823	Mouse	PMID:14976402
Biological Process	GO:0070588	calcium ion transmembrane transport	Cacna1e	IMP	MGI:MGI:2451031	Mouse	PMID:11854466
Biological Process	GO:0070588	calcium ion transmembrane transport	Cacna1e	IMP	MGI:MGI:3526823	Mouse	PMID:15630454
Biological Process	GO:0070588	calcium ion transmembrane transport	Cacna1e	IMP	MGI:MGI:3526823	Mouse	PMID:17369816
Biological Process	GO:0070588	calcium ion transmembrane transport	Cacna1e	IMP	MGI:MGI:2179732	Mouse	PMID:11959138
Biological Process	GO:0006816	calcium ion transport	Cacna1e	IMP		Mouse	PMID:12827191
Biological Process	GO:0051649	establishment of localization in cell	Cacna1e	IMP	MGI:MGI:2451031	Mouse	PMID:11854466
Biological Process	GO:0051649	establishment of localization in cell	Cacna1e	IMP	MGI:MGI:3526823	Mouse	PMID:17369816
Biological Process	GO:0051649	establishment of localization in cell	Cacna1e	IMP		Mouse	PMID:12074836
Biological Process	GO:0051649	establishment of localization in cell	Cacna1e	IMP	MGI:MGI:2179732	Mouse	PMID:11959138
Biological Process	GO:0051649	establishment of localization in cell	Cacna1e	IMP	MGI:MGI:3526823	Mouse	PMID:15630454
Biological Process	GO:0042596	fear response	Cacna1e	IMP	MGI:MGI:2179732	Mouse	PMID:10801976
Biological Process	GO:0030317	flagellated sperm motility	Cacna1e	IMP	MGI:MGI:2179732	Mouse	PMID:11959138
Biological Process	GO:0042593	glucose homeostasis	Cacna1e	IMP	MGI:MGI:2179732	Mouse	PMID:11735114
Biological Process	GO:0042593	glucose homeostasis	Cacna1e	IMP	MGI:MGI:3526823	Mouse	PMID:11923483
Biological Process	GO:0007626	locomotory behavior	Cacna1e	IMP	MGI:MGI:2179732	Mouse	PMID:10801976
Biological Process	GO:0050877	nervous system process	Cacna1e	IMP	MGI:MGI:3526823	Mouse	PMID:17376845
Biological Process	GO:0002027	regulation of heart rate	Cacna1e	IMP	MGI:MGI:3526823	Mouse	PMID:14976402
Biological Process	GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus	Cacna1e	IMP	MGI:MGI:3526823	Mouse	PMID:11923483
Biological Process	GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus	Cacna1e	IMP	MGI:MGI:3526823	Mouse	PMID:15630454
Biological Process	GO:0090273	regulation of somatostatin secretion	Cacna1e	IMP	MGI:MGI:3526823	Mouse	PMID:17369816
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	Cacna1e	EXP		Rat	PMID:19193890|RGD:13792544
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	Cacna1e	IDA		Rat	PMID:19193890|RGD:13792544
Biological Process	GO:0048265	response to pain	Cacna1e	IMP		Mouse	PMID:12074836
Biological Process	GO:0019233	sensory perception of pain	Cacna1e	IMP	MGI:MGI:3526823	Mouse	PMID:19726083
Biological Process	GO:0019226	transmission of nerve impulse	Cacna1e	IMP		Mouse	PMID:19193890
Biological Process	GO:0008542	visual learning	Cacna1e	IMP	MGI:MGI:2179732	Mouse	PMID:11263998

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern