Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes C5AR2
  • Mouse genes C5ar2
  • Rat genes C5ar2
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set C5ar2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	C5AR2	IPI	UniProtKB:P01024	Human	PMID:12540846
Molecular Function	GO:0005515	protein binding	C5AR2	IPI	UniProtKB:Q9UHG0	Human	PMID:32296183
Cellular Component	GO:0045177	apical part of cell	C5AR2	IDA		Human	PMID:22496247
Cellular Component	GO:0009925	basal plasma membrane	C5AR2	IDA		Human	PMID:22960554
Biological Process	GO:0032715	negative regulation of interleukin-6 production	C5AR2	IMP		Human	PMID:16204243
Biological Process	GO:0090024	negative regulation of neutrophil chemotaxis	C5AR2	IMP		Human	PMID:16204243
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	C5AR2	IMP		Human	PMID:16204243
Biological Process	GO:0032677	regulation of interleukin-8 production	C5AR2	IMP		Human	PMID:22496247

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern