Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BUB1B
  • Mouse genes Bub1b
  • Rat genes Bub1b
  • Zfish genes bub1ba,bub1bb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Bub1b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	BUB1B	IPI	UniProtKB:Q12834	Human	PMID:11030144
Molecular Function	GO:0005515	protein binding	BUB1B	IPI	UniProtKB:Q12834	Human	PMID:15525512
Molecular Function	GO:0005515	protein binding	BUB1B	IPI	UniProtKB:P53350	Human	PMID:16760428
Molecular Function	GO:0005515	protein binding	BUB1B	IPI	UniProtKB:Q8NG31	Human	PMID:17981135
Molecular Function	GO:0005515	protein binding	BUB1B	IPI	UniProtKB:O43684	Human	PMID:19407811
Molecular Function	GO:0005515	protein binding	BUB1B	IPI	UniProtKB:P0CG48	Human	PMID:19407811
Molecular Function	GO:0005515	protein binding	BUB1B	IPI	UniProtKB:Q12834	Human	PMID:19407811
Molecular Function	GO:0005515	protein binding	BUB1B	IPI	UniProtKB:Q92831	Human	PMID:19407811
Molecular Function	GO:0005515	protein binding	BUB1B	IPI	UniProtKB:Q12834	Human	PMID:20212161
Molecular Function	GO:0005515	protein binding	BUB1B	IPI	UniProtKB:Q13257	Human	PMID:20212161
Molecular Function	GO:0005515	protein binding	BUB1B	IPI	UniProtKB:O43683	Human	PMID:20360068
Molecular Function	GO:0005515	protein binding	BUB1B	IPI	UniProtKB:Q12834	Human	PMID:20360068
Molecular Function	GO:0005515	protein binding	BUB1B	IPI	UniProtKB:Q12834	Human	PMID:21300909
Molecular Function	GO:0005515	protein binding	BUB1B	IPI	UniProtKB:Q13257	Human	PMID:21300909
Molecular Function	GO:0005515	protein binding	BUB1B	IPI	UniProtKB:Q12834	Human	PMID:21407176
Molecular Function	GO:0005515	protein binding	BUB1B	IPI	UniProtKB:Q13257	Human	PMID:21772247
Molecular Function	GO:0005515	protein binding	BUB1B	IPI	UniProtKB:O43684	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	BUB1B	IPI	UniProtKB:O43684	Human	PMID:22000412
Molecular Function	GO:0005515	protein binding	BUB1B	IPI	UniProtKB:Q12834	Human	PMID:22000412
Molecular Function	GO:0005515	protein binding	BUB1B	IPI	UniProtKB:Q13257	Human	PMID:22000412
Molecular Function	GO:0005515	protein binding	BUB1B	IPI	UniProtKB:Q8NG31-2	Human	PMID:22000412
Molecular Function	GO:0005515	protein binding	BUB1B	IPI	UniProtKB:Q12834	Human	PMID:24581499
Molecular Function	GO:0005515	protein binding	BUB1B	IPI	UniProtKB:P45481	Human	PMID:24825348
Molecular Function	GO:0005515	protein binding	BUB1B	IPI	UniProtKB:Q8IXJ6	Human	PMID:24825348
Molecular Function	GO:0005515	protein binding	BUB1B	IPI	UniProtKB:Q92831	Human	PMID:24825348
Molecular Function	GO:0005515	protein binding	BUB1B	IPI	UniProtKB:Q12834	Human	PMID:25241761
Molecular Function	GO:0005515	protein binding	BUB1B	IPI	UniProtKB:O43684	Human	PMID:25383541
Molecular Function	GO:0005515	protein binding	BUB1B	IPI	UniProtKB:Q12834	Human	PMID:25383541
Molecular Function	GO:0005515	protein binding	BUB1B	IPI	UniProtKB:Q13257	Human	PMID:25383541
Molecular Function	GO:0005515	protein binding	BUB1B	IPI	UniProtKB:O43684	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BUB1B	IPI	UniProtKB:Q12834	Human	PMID:25502805
Molecular Function	GO:0005515	protein binding	BUB1B	IPI	UniProtKB:O43683	Human	PMID:25852190
Molecular Function	GO:0005515	protein binding	BUB1B	IPI	UniProtKB:O43684	Human	PMID:25852190
Molecular Function	GO:0005515	protein binding	BUB1B	IPI	UniProtKB:Q12834	Human	PMID:25852190
Molecular Function	GO:0005515	protein binding	BUB1B	IPI	UniProtKB:Q13257	Human	PMID:25852190
Molecular Function	GO:0005515	protein binding	BUB1B	IPI	UniProtKB:O43684	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	BUB1B	IPI	UniProtKB:Q9Y572	Human	PMID:29883609
Molecular Function	GO:0005515	protein binding	BUB1B	IPI	UniProtKB:O43683	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	BUB1B	IPI	UniProtKB:Q12834	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	BUB1B	IPI	UniProtKB:O43684	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	BUB1B	IPI	UniProtKB:Q12834	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	BUB1B	IPI	UniProtKB:O43684	Human	PMID:9660858
Molecular Function	GO:0005515	protein binding	BUB1B	IPI	UniProtKB:Q02224	Human	PMID:9763420
Molecular Function	GO:0005515	protein binding	Bub1b	IPI	UniProtKB:Q6RT24	Mouse	MGI:MGI:2673075|PMID:12925705
Cellular Component	GO:0005737	cytoplasm	BUB1B	IDA		Human	GO_REF:0000054
Cellular Component	GO:0005829	cytosol	BUB1B	IDA		Human	GO_REF:0000052
Cellular Component	GO:0000776	kinetochore	BUB1B	IDA		Human	PMID:12925705
Cellular Component	GO:0000776	kinetochore	BUB1B	IDA		Human	PMID:17363900
Cellular Component	GO:0000776	kinetochore	BUB1B	IDA		Human	PMID:17227893
Cellular Component	GO:0000776	kinetochore	BUB1B	IDA		Human	PMID:19465021
Cellular Component	GO:0000776	kinetochore	BUB1B	IDA		Human	PMID:22331848
Cellular Component	GO:0000776	kinetochore	BUB1B	IDA		Human	PMID:9660858
Cellular Component	GO:0000776	kinetochore	BUB1B	IDA		Human	PMID:9763420
Cellular Component	GO:0000776	kinetochore	Bub1b	IDA		Mouse	MGI:MGI:2673075|PMID:12925705
Cellular Component	GO:0000776	kinetochore	Bub1b	IDA		Mouse	PMID:15226446
Cellular Component	GO:0000776	kinetochore	Bub1b	IDA		Mouse	PMID:17938250
Cellular Component	GO:0000776	kinetochore	Bub1b	IDA		Mouse	PMID:18765791
Cellular Component	GO:0000776	kinetochore	Bub1b	IDA		Mouse	PMID:32284991
Cellular Component	GO:0000776	kinetochore	Bub1b	IMP		Mouse	PMID:17227893
Cellular Component	GO:0033597	mitotic checkpoint complex	BUB1B	IPI		Human	PMID:27509861
Cellular Component	GO:0000940	outer kinetochore	BUB1B	IDA		Human	PMID:19468067
Cellular Component	GO:0000940	outer kinetochore	Bub1b	IDA		Mouse	PMID:14519686
Cellular Component	GO:0000940	outer kinetochore	Bub1b	IDA		Mouse	PMID:19283064
Cellular Component	GO:0048471	perinuclear region of cytoplasm	BUB1B	IDA		Human	PMID:20531406
Cellular Component	GO:0005819	spindle	BUB1B	IDA		Human	PMID:9763420
Biological Process	GO:0007091	metaphase/anaphase transition of mitotic cell cycle	Bub1b	IGI	MGI:MGI:88039	Mouse	PMID:15767571
Biological Process	GO:0007094	mitotic spindle assembly checkpoint signaling	BUB1B	IDA		Human	PMID:10477750
Biological Process	GO:0051444	negative regulation of ubiquitin-protein transferase activity	BUB1B	IDA		Human	PMID:11535616
Biological Process	GO:0071459	protein localization to chromosome, centromeric region	Bub1b	IMP		Mouse	PMID:19283064

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern