Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BTLA
  • Mouse genes Btla
  • Rat genes Btla
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Btla

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	BTLA	IPI	UniProtKB:Q92956	Human	PMID:27152329
Molecular Function	GO:0005515	protein binding	Btla	IPI	PR:Q80WM9	Mouse	PMID:15568026
Molecular Function	GO:0005515	protein binding	Btla	IPI	PR:P97797	Mouse	PMID:12796776
Molecular Function	GO:0005515	protein binding	Btla	IPI	PR:P35235	Mouse	PMID:15568026
Molecular Function	GO:0005515	protein binding	Btla	IPI	PR:P35235	Mouse	PMID:12796776
Molecular Function	GO:0038023	signaling receptor activity	Btla	IGI	MGI:MGI:3039619	Mouse	PMID:12920180
Cellular Component	GO:0009897	external side of plasma membrane	Btla	IDA		Mouse	PMID:15568026
Cellular Component	GO:0005886	plasma membrane	Btla	IDA		Mouse	PMID:12796776
Biological Process	GO:0007166	cell surface receptor signaling pathway	Btla	IDA		Mouse	PMID:15568026
Biological Process	GO:0002768	immune response-regulating cell surface receptor signaling pathway	Btla	IMP	MGI:MGI:3027713	Mouse	PMID:15568026
Biological Process	GO:0046642	negative regulation of alpha-beta T cell proliferation	Btla	IMP	MGI:MGI:3027713	Mouse	PMID:15568026
Biological Process	GO:0030889	negative regulation of B cell proliferation	Btla	IMP	MGI:MGI:3027713	Mouse	PMID:12796776
Biological Process	GO:0042130	negative regulation of T cell proliferation	Btla	IMP	MGI:MGI:3027713	Mouse	PMID:12796776

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern