Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BSCL2
  • Mouse genes Bscl2
  • Rat genes Bscl2
  • Zfish genes bscl2,bscl2l
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Bscl2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005543	phospholipid binding	BSCL2	IDA		Human	PMID:30293840
Molecular Function	GO:0005515	protein binding	BSCL2	IPI	UniProtKB:Q96HH6	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	BSCL2	IPI	UniProtKB:Q9BZL3	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	BSCL2	IPI	UniProtKB:Q96HH6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BSCL2	IPI	UniProtKB:Q9BZL3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BSCL2	IPI	UniProtKB:Q96B96	Human	PMID:30901948
Molecular Function	GO:0005515	protein binding	BSCL2	IPI	UniProtKB:Q9HBF4	Human	PMID:30970241
Molecular Function	GO:0005515	protein binding	BSCL2	IPI	UniProtKB:Q9NP72	Human	PMID:30970241
Molecular Function	GO:0005515	protein binding	BSCL2	IPI	UniProtKB:Q96B96	Human	PMID:31708432
Molecular Function	GO:0005515	protein binding	Bscl2	IPI	UniProtKB:Q8K2C8	Mouse	PMID:27806294
Molecular Function	GO:0005515	protein binding	Bscl2	IPI	UniProtKB:Q8C0N2	Mouse	PMID:27806294
Cellular Component	GO:0005783	endoplasmic reticulum	Bscl2	IDA		Mouse	PMID:18585921
Cellular Component	GO:0005783	endoplasmic reticulum	Bscl2	IDA		Mouse	PMID:23458123
Cellular Component	GO:0005789	endoplasmic reticulum membrane	BSCL2	IDA		Human	PMID:14981520
Cellular Component	GO:0005789	endoplasmic reticulum membrane	BSCL2	IDA		Human	PMID:27879284
Cellular Component	GO:0005789	endoplasmic reticulum membrane	BSCL2	IDA		Human	PMID:30901948
Cellular Component	GO:0005789	endoplasmic reticulum membrane	BSCL2	IDA		Human	PMID:31708432
Cellular Component	GO:0005811	lipid droplet	BSCL2	IDA		Human	PMID:27879284
Cellular Component	GO:0005811	lipid droplet	BSCL2	IDA		Human	PMID:30970241
Biological Process	GO:0060612	adipose tissue development	Bscl2	IMP	MGI:MGI:5014325	Mouse	PMID:21551454
Biological Process	GO:0061725	cytosolic lipolysis	Bscl2	IMP	MGI:MGI:2386686,MGI:MGI:5629937	Mouse	PMID:24622797
Biological Process	GO:0045444	fat cell differentiation	Bscl2	IMP		Mouse	MGI:MGI:5319118|PMID:22269949
Biological Process	GO:0045444	fat cell differentiation	Bscl2	IMP		Mouse	PMID:23458123
Biological Process	GO:0140042	lipid droplet formation	BSCL2	IMP		Human	PMID:27564575
Biological Process	GO:0140042	lipid droplet formation	BSCL2	IMP		Human	PMID:27879284
Biological Process	GO:0140042	lipid droplet formation	BSCL2	IDA		Human	PMID:31178403
Biological Process	GO:0140042	lipid droplet formation	BSCL2	IDA		Human	PMID:31708432
Biological Process	GO:0140042	lipid droplet formation	Bscl2	IDA		Mouse	PMID:23458123
Biological Process	GO:0034389	lipid droplet organization	BSCL2	IMP		Human	PMID:19278620
Biological Process	GO:0034389	lipid droplet organization	Bscl2	IMP	MGI:MGI:5014325	Mouse	PMID:27806294
Biological Process	GO:0034389	lipid droplet organization	Bscl2	IMP	MGI:MGI:5014325	Mouse	PMID:24778225
Biological Process	GO:0019915	lipid storage	BSCL2	IMP		Human	PMID:19278620
Biological Process	GO:0019915	lipid storage	Bscl2	IMP		Mouse	PMID:23458123
Biological Process	GO:0051651	maintenance of location in cell	Bscl2	IMP		Mouse	PMID:23458123
Biological Process	GO:0043086	negative regulation of catalytic activity	Bscl2	IMP	MGI:MGI:5014325	Mouse	PMID:27806294
Biological Process	GO:0050995	negative regulation of lipid catabolic process	Bscl2	IMP		Mouse	MGI:MGI:5319118|PMID:22269949
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	Bscl2	IMP		Mouse	MGI:MGI:6101101|PMID:27748422
Biological Process	GO:1905693	regulation of phosphatidic acid biosynthetic process	Bscl2	IMP	MGI:MGI:5014325	Mouse	PMID:27806294
Biological Process	GO:0048515	spermatid differentiation	Bscl2	IMP	MGI:MGI:3757577,MGI:MGI:5629937	Mouse	PMID:24778225

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern