Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BFAR
  • Mouse genes Bfar
  • Rat genes Bfar
  • Zfish genes pphln1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Bfar

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0089720	caspase binding	BFAR	IDA		Human	PMID:10716992
Molecular Function	GO:0005515	protein binding	BFAR	IPI	UniProtKB:P55061	Human	PMID:21068390
Molecular Function	GO:0005515	protein binding	BFAR	IPI	UniProtKB:P61086	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BFAR	IPI	UniProtKB:P61086	Human	PMID:32814053
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	BFAR	IDA		Human	PMID:10716992
Molecular Function	GO:0061630	ubiquitin protein ligase activity	BFAR	IDA		Human	PMID:21068390
Cellular Component	GO:0005783	endoplasmic reticulum	BFAR	IDA		Human	PMID:21068390
Cellular Component	GO:0016020	membrane	BFAR	IDA		Human	PMID:10716992
Biological Process	GO:0043066	negative regulation of apoptotic process	BFAR	IDA		Human	PMID:10716992
Biological Process	GO:1903895	negative regulation of IRE1-mediated unfolded protein response	BFAR	IMP		Human	PMID:21068390
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	BFAR	IDA		Human	PMID:21068390
Biological Process	GO:0051865	protein autoubiquitination	BFAR	IDA		Human	PMID:21068390
Biological Process	GO:0070936	protein K48-linked ubiquitination	BFAR	IDA		Human	PMID:21068390
Biological Process	GO:0070534	protein K63-linked ubiquitination	BFAR	IDA		Human	PMID:21068390
Biological Process	GO:0000209	protein polyubiquitination	BFAR	IDA		Human	PMID:21068390
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	BFAR	IDA		Human	PMID:21068390

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern