Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BEST1
  • Mouse genes Best1
  • Rat genes Best1
  • Zfish genes best1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Best1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005254	chloride channel activity	BEST1	IDA		Human	PMID:17003041
Molecular Function	GO:0042802	identical protein binding	BEST1	IPI	UniProtKB:O76090	Human	PMID:19372599
Cellular Component	GO:0009925	basal plasma membrane	BEST1	IDA		Human	PMID:31791063
Cellular Component	GO:0016323	basolateral plasma membrane	BEST1	IDA		Human	PMID:11050159
Cellular Component	GO:0016323	basolateral plasma membrane	BEST1	IDA		Human	PMID:19853238
Cellular Component	GO:0034707	chloride channel complex	BEST1	IDA		Human	PMID:17003041
Biological Process	GO:0006821	chloride transport	BEST1	IDA		Human	PMID:17003041
Biological Process	GO:0050908	detection of light stimulus involved in visual perception	Best1	IMP	MGI:MGI:3795281	Mouse	PMID:16636205
Biological Process	GO:0051924	regulation of calcium ion transport	Best1	IMP	MGI:MGI:3795281	Mouse	PMID:16636205
Biological Process	GO:0030321	transepithelial chloride transport	BEST1	IDA		Human	PMID:17003041

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern